Figure 2From: Chronic asymptomatic pyuria precedes overt urinary tract infection and deterioration of renal function in autosomal dominant polycystic kidney disease Renal outcomes of patients according to asymptomatic pyuria. There was no significant difference between group A and group B in initial eGFR (92.5 ± 27.1 vs. 88.7 ± 32.5 ml/min/1.73m2; P=0.35). However, the final eGFR was significantly lower in group B than in group A (63.3 ± 37.0 vs. 85.5 ± 31.7 ml/min/1.73m2; P<0.001). Moreover, ΔeGFR was larger in group B than in group A (-2.7 ± 4.56 vs. -1.17 ± 5.8 ml/min/1.73m2 per year, respectively; P=0.01). The incidence of ESRD was also significantly higher in group B than in group A (n = 15, 16.0% vs. n=7, 4.3%; P=0.001). eGFR, estimated glomerular filtration rate; ESRD, end-stage renal disease.Back to article page