Chronic asymptomatic pyuria precedes overt urinary tract infection and deterioration of renal function in autosomal dominant polycystic kidney disease

Table 6 Independent factors associated with the annual change of ΔGFR

Variable	B*	95% CI for B		P-value
		Lower	Upper
Age	-0.081	-0.133	-0.030	0.002
HTN (initial)	-2.394	-3.767	-1.021	0.001
DM (initial)	-6.076	-12.246	0.095	NS
Group B^†	-1.530	-2.904	-0.155	0.03
Overt UTI^†	-2.162	-4.140	-0.184	0.03

Analyzed by multiple linear regression model, R ² = 0.101 for 3 covariates with Group B, R ² = 0.093 for 3 covariates with Overt UTI. The age, initial HTN and initial DM were analyzed as covariates with Group B or Overt UTI.
*B: Unstandardized coefficients.
^† Age, initial HTN and initial DM were analyzed as covariates with Group B or Overt UTI.
ΔGFR, annual reduction rate of glomerular filtration rate; CI, confidence interval; DM, diabetes mellitus; HTN, hypertension; UTI, urinary tract infection.

ISSN: 1471-2369