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Table 1 Characteristics among patients discharged on clopidogrel at hospital discharge by eGFR strata

From: Chronic kidney disease is associated with adverse outcomes among elderly patients taking clopidogrel after hospitalization for acute coronary syndrome

 

Overall (n = 7413)

eGFR > = 60 ml/min/m2 (n = 3997)

eGFR 30–60 ml/min/m2 (n = 2559)

eGFR < 30 ml/min/m2 (n = 857)

p-value

Age (mean +/− SD)

66.3 (11.2)

61.9 (9.9)

71.2 (10.5)

71.9 (10.5)

<0.001

Male sex (%, n)

98 (7294)

98 (3936)

98 (2513)

99 (845)

0.61

White race (%, n)

80 (5963)

82 (3269)

81 (2083)

71 (611)

<0.001

Medical conditions (%, n)

  Diabetes

42 (3139)

35 (1385)

47 (1209)

64 (545)

<0.001

  Hypertension

28 (2101)

21 (843)

33 (840)

49 (418)

<0.001

  H/o MI

19 (1410)

17 (692)

21 (544)

20 (174)

<0.001

  CHF

13 (999)

6 (227)

18 (453)

37 (319)

<0.001

  Stroke

2 (172)

2 (65)

3 (75)

4 (32)

<0.001

  PAD

13 (974)

10 (398)

15 (395)

21 (181)

<0.001

  Lipid disorder

76 (5627)

77 (3070)

77 (1976)

68 (581)

<0.001

  Liver disease

2 (177)

3 (108)

2 (50)

2 (19)

0.15

  COPD

12 (902)

11 (439)

14 (355)

13 (108)

.002

  Cancer

5 (388)

5 (182)

6 (155)

6 (51)

.017

  Dementia

4 (309)

4 (152)

5 (119)

4 (38)

0.226

  Depression

9 (642)

10 (399)

8 (196)

5 (47)

<0.001

Current smoker (%, n)

31 (2333)

42 (1681)

21 (537)

13 (115)

<0.001

LVEF (%, n)

    

<0.001

  EF > = 40%

73 (5430)

78 (3121)

70 (1786)

61 (523)

 

  EF < 40%

22 (1622)

16 (630)

27 (688)

35 (304)

 

  missing

5 (361)

6 (246)

3 (85)

4 (30)

 

Procedure (%, n)

    

<0.001

  No PCI

41 (2990)

31 (1215)

47 (1208)

66 (567)

 

  PCI/no stent

2 (175)

3 (109)

2 (47)

2 (19)

 

  PCI/BMS

13 (929)

14 (540)

12 (311)

9 (78)

 

  PCI/DES

45 (3287)

53 (2111)

39 (984)

22 (192)

 

TIMI > = 3 (%, n)

59 (4371)

48 (1901)

71 (1821)

76 (649)

<0.001

Glycoprotein inhibitor (%, n)

46 (3394)

53 (2130)

41 (1059)

24 (205)

 

Hospital discharge medications (%, n)

  ASA

95 (7016)

96 (3821)

94 (2404)

92 (791)

<0.001

  Beta-blocker

93 (6925)

94 (3752)

93 (2375)

93 (798)

0.223

  ACE-I

71 (5276)

77 (3068)

70 (1799)

48 (409)

<0.001

  ARB

9 (644)

6 (256)

11 (280)

13 (108)

<0.001

  heparin

4 (264)

4 (142)

4 (100)

3 (22)

0.186