From: Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy
Characteristic | DN Case (n = 700) | Control (n = 732) |
---|---|---|
Male; n (%) | 405 (57.8%) | 306 (41.8%) |
Age at diagnosis of T1D (yr) | 14.7 ± 7.6 | 15.4 ± 7.9 |
Duration of T1D (yr)a | 33 ± 9.3 | 28.1 ± 9 |
HbA1c (%)b | 9 ± 1.9 | 8.6 ± 1.5 |
Systolic blood pressure (mmHg)b | 144.9 ± 20.9 | 125.1 ± 14.8 |
Diastolic blood pressure (mmHg)b | 81.5 ± 11.4 | 75.5 ± 7.7 |
Body mass index (kg/m2) | 26.3 ± 4.8 | 26.1 ± 4.2 |
Serum cholesterol (mmol/L) | 5.3 ± 1.2 | 5.1 ± 0.9 |
Serum creatinine (umol/L)c; median (interquartile range) | 130 (102–182.5) | 92 (78.8 - 105) |
Glomerular filtration rate (ml/min/1.73m2)c; median (interquartile range) | 47.8 (33.6 - 66.2) | 70 (59.3 - 85.5) |
End-stage renal disease n (%) | 186 (26.6%) | NA |