From: Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy
Chra | Position | Gene | SNP ID | Allele | Case count | MAF | Control count | MAF | ORb | C.I.c | Pd |
---|---|---|---|---|---|---|---|---|---|---|---|
2 | 219428221 | WNT6 | rs940469 | [T/C] | 24/170/483 | 0.16 | 24/170/483 | 0.18 | 0.86 | 0.67 - 1.11 | 0.25 |
2 | 219430908 | WNT6 | rs690877 | [T/C] | 56/276/360 | 0.28 | 56/276/360 | 0.27 | 0.92 | 0.74 - 1.14 | 0.43 |
2 | 219440386 | WNT6 | rs6754599 | [G/C] | 18/166/494 | 0.15 | 18/166/494 | 0.17 | 0.85 | 0.65 - 1.11 | 0.22 |
2 | 219458990 | WNT6 | rs2385199 | [G/A] | 23/200/471 | 0.18 | 23/200/471 | 0.19 | 0.90 | 0.7 - 1.16 | 0.43 |
3 | 41205327 | CTNNB1 | rs2691678 | [C/T] | 51/250/390 | 0.25 | 51/250/390 | 0.25 | 1.01 | 0.81 - 1.26 | 0.91 |
3 | 41243358 | CTNNB1 | rs11564447 | [G/T] | 1/59/634 | 0.04 | 1/59/634 | 0.04 | 0.91 | 0.57 - 1.43 | 0.68 |
3 | 41254444 | CTNNB1 | rs4135385 | [G/A] | 49/237/398 | 0.24 | 49/237/398 | 0.23 | 1.04 | 0.84 - 1.3 | 0.70 |
3 | 55450313 | WNT5A | rs815533 | [A/G] | 22/206/466 | 0.18 | 22/206/466 | 0.17 | 1.27 | 0.99 - 1.64 | 0.06 |
3 | 55456115 | WNT5A | rs3913369 | [T/G] | 33/261/394 | 0.24 | 33/261/394 | 0.23 | 0.91 | 0.72 - 1.14 | 0.40 |
3 | 55466053 | WNT5A | rs629537 | [A/G] | 11/145/534 | 0.12 | 11/145/534 | 0.13 | 0.89 | 0.67 - 1.18 | 0.40 |
3 | 55467090 | WNT5A | rs845542 | [C/T] | 44/272/377 | 0.26 | 44/272/377 | 0.25 | 1.19 | 0.95 - 1.49 | 0.13 |
3 | 55494897 | WNT5A | rs648872 | [T/C] | 13/172/501 | 0.14 | 13/172/501 | 0.17 | 0.86 | 0.67 - 1.1 | 0.22 |
3 | 55495818 | WNT5A | rs566926 | [T/G] | 49/252/368 | 0.26 | 49/252/368 | 0.27 | 0.99 | 0.8 - 1.24 | 0.96 |
3 | 121016036 | GSK3B | rs11917714 | [T/C] | 19/205/470 | 0.18 | 19/205/470 | 0.16 | 1.02 | 0.79 - 1.31 | 0.89 |
3 | 121018485 | GSK3B | rs11929668 | [G/C] | 22/170/501 | 0.15 | 22/170/501 | 0.18 | 0.87 | 0.67 - 1.12 | 0.27 |
3 | 121133839 | GSK3B | rs17204365 | [C/T] | 2/41/648 | 0.03 | 2/41/648 | 0.03 | 1.61 | 0.91 - 2.85 | 0.10 |
3 | 121157741 | GSK3B | rs17810235 | [T/C] | 74/303/312 | 0.33 | 74/303/312 | 0.29 | 1.33 | 1.09 - 1.64 | 0.01 |
3 | 121300363 | GSK3B | rs17471 | [A/T] | 3/110/581 | 0.08 | 3/110/581 | 0.09 | 0.67 | 0.47 - 0.95 | 0.02 |
3 | 121306727 | GSK3B | rs11927974 | [A/G] | 8/101/584 | 0.08 | 8/101/584 | 0.09 | 0.98 | 0.71 - 1.35 | 0.89 |
3 | 121307901 | GSK3B | rs334538 | [A/G] | 22/191/481 | 0.17 | 22/191/481 | 0.19 | 0.89 | 0.7 - 1.14 | 0.35 |
3 | 121308854 | GSK3B | rs12053912 | [T/A] | 17/186/485 | 0.16 | 17/186/485 | 0.14 | 1.21 | 0.92 - 1.58 | 0.18 |
3 | 121315311 | GSK3B | rs334543 | [C/A] | 66/311/307 | 0.32 | 66/311/307 | 0.35 | 0.79 | 0.65 - 0.97 | 0.02 |
4 | 108055760 | DKK2 | rs429941 | [G/A] | 53/282/356 | 0.28 | 53/282/356 | 0.28 | 1.08 | 0.88 - 1.34 | 0.46 |
4 | 108062942 | DKK2 | rs10488898 | [A/G] | 2/77/603 | 0.06 | 2/77/603 | 0.07 | 0.85 | 0.58 - 1.24 | 0.40 |
4 | 108065243 | DKK2 | rs17037102 | [A/G] | 7/132/526 | 0.11 | 7/132/526 | 0.10 | 1.17 | 0.85 - 1.6 | 0.34 |
4 | 108084260 | DKK2 | rs10488899 | [G/T] | 42/237/410 | 0.23 | 42/237/410 | 0.21 | 1.10 | 0.88 - 1.39 | 0.40 |
4 | 108110470 | DKK2 | rs17509845 | [A/G] | 1/66/622 | 0.05 | 1/66/622 | 0.05 | 1.08 | 0.69 - 1.7 | 0.74 |
4 | 108120464 | DKK2 | rs17618172 | [G/A] | 20/219/445 | 0.19 | 20/219/445 | 0.20 | 1.01 | 0.79 - 1.28 | 0.96 |
4 | 108135958 | DKK2 | rs7690634 | [A/T] | 9/165/515 | 0.13 | 9/165/515 | 0.12 | 1.19 | 0.89 - 1.58 | 0.24 |
4 | 108165736 | DKK2 | rs4956277 | [C/A] | 30/246/396 | 0.23 | 30/246/396 | 0.24 | 0.94 | 0.75 - 1.17 | 0.58 |
4 | 108170809 | DKK2 | rs10021344 | [G/A] | 150/357/185 | 0.47 | 150/357/185 | 0.48 | 0.99 | 0.82 - 1.19 | 0.88 |
4 | 108173328 | DKK2 | rs956137 | [A/C] | 4/111/577 | 0.09 | 4/111/577 | 0.08 | 1.28 | 0.92 - 1.8 | 0.15 |
4 | 108173463 | DKK2 | rs6827902 | [C/A] | 28/237/416 | 0.22 | 28/237/416 | 0.21 | 1.15 | 0.91 - 1.45 | 0.23 |
4 | 108181414 | DKK2 | rs6823507 | [C/T] | 1/88/593 | 0.07 | 1/88/593 | 0.08 | 0.87 | 0.6 - 1.26 | 0.46 |
4 | 108185493 | DKK2 | rs419178 | [C/T] | 38/272/379 | 0.25 | 38/272/379 | 0.27 | 0.86 | 0.69 - 1.07 | 0.17 |
4 | 108199999 | DKK2 | rs398093 | [T/C] | 12/138/510 | 0.12 | 12/138/510 | 0.12 | 1.09 | 0.81 - 1.46 | 0.58 |
4 | 108200154 | DKK2 | rs17510191 | [C/T] | 20/251/423 | 0.21 | 20/251/423 | 0.18 | 1.13 | 0.89 - 1.43 | 0.31 |
7 | 120727672 | WNT16 | rs2707521 | [T/C] | 103/338/239 | 0.40 | 103/338/239 | 0.41 | 0.90 | 0.74 - 1.1 | 0.32 |
7 | 120738146 | WNT16 | rs13247600 | [C/G] | 3/81/610 | 0.06 | 3/81/610 | 0.07 | 1.08 | 0.74 - 1.57 | 0.69 |
7 | 120738380 | WNT16 | rs2707520 | [G/T] | 166/340/183 | 0.49 | 166/340/183 | 0.49 | 1.12 | 0.92 - 1.35 | 0.25 |
7 | 120741508 | WNT16 | rs983926 | [A/G] | 6/101/587 | 0.08 | 6/101/587 | 0.09 | 0.93 | 0.67 - 1.3 | 0.68 |
7 | 120751201 | WNT16 | rs3757552 | [C/T] | 9/151/534 | 0.12 | 9/151/534 | 0.12 | 0.89 | 0.67 - 1.19 | 0.44 |
7 | 120762001 | WNT16 | rs3801387 | [C/T] | 69/283/340 | 0.30 | 69/283/340 | 0.29 | 1.00 | 0.81 - 1.23 | 0.99 |
7 | 120774586 | WNT16 | rs2707461 | [T/C] | 18/187/489 | 0.16 | 18/187/489 | 0.17 | 0.98 | 0.77 - 1.26 | 0.89 |
14 | 58696138 | DAAM1 | rs8016068 | [T/C] | 4/176/514 | 0.13 | 4/176/514 | 0.12 | 1.09 | 0.81 - 1.47 | 0.57 |
14 | 58713714 | DAAM1 | rs17095819 | [G/A] | 15/185/477 | 0.16 | 15/185/477 | 0.13 | 1.28 | 0.96 - 1.71 | 0.09 |
14 | 58728544 | DAAM1 | rs1252906 | [G/T] | 19/164/511 | 0.15 | 19/164/511 | 0.18 | 0.75 | 0.58 - 0.97 | 0.03 |
14 | 58826755 | DAAM1 | rs7155987 | [T/C] | 18/180/496 | 0.16 | 18/180/496 | 0.14 | 1.10 | 0.84 - 1.44 | 0.48 |
14 | 58833620 | DAAM1 | rs12878138 | [T/C] | 2/99/593 | 0.07 | 2/99/593 | 0.07 | 0.96 | 0.67 - 1.39 | 0.84 |
14 | 58861382 | DAAM1 | rs941882 | [C/A] | 40/238/416 | 0.23 | 40/238/416 | 0.23 | 1.03 | 0.82 - 1.28 | 0.82 |
14 | 58885779 | DAAM1 | rs17834014 | [G/A] | 3/86/605 | 0.07 | 3/86/605 | 0.08 | 0.97 | 0.67 - 1.42 | 0.88 |
14 | 58886484 | DAAM1 | rs12880248 | [A/G] | 12/177/505 | 0.14 | 12/177/505 | 0.14 | 1.06 | 0.8 - 1.39 | 0.70 |
14 | 58889427 | DAAM1 | rs12878070 | [G/T] | 150/334/210 | 0.46 | 150/334/210 | 0.42 | 1.10 | 0.91 - 1.32 | 0.33 |
14 | 58908520 | DAAM1 | rs17096179 | [C/A] | 5/104/585 | 0.08 | 5/104/585 | 0.09 | 0.88 | 0.63 - 1.24 | 0.47 |
14 | 58913159 | DAAM1 | rs1253192 | [A/G] | 5/80/609 | 0.06 | 5/80/609 | 0.09 | 0.65 | 0.46 - 0.93 | 0.02 |
16 | 275374 | AXIN1 | rs2685127 | [T/C] | 7/157/529 | 0.12 | 7/157/529 | 0.13 | 1.02 | 0.76 - 1.36 | 0.92 |
16 | 276397 | AXIN1 | rs400037 | [T/C] | 32/243/410 | 0.22 | 32/243/410 | 0.22 | 0.97 | 0.77 - 1.21 | 0.77 |
16 | 281080 | AXIN1 | rs12925669 | [A/G] | 22/171/501 | 0.15 | 22/171/501 | 0.16 | 1.06 | 0.82 - 1.37 | 0.65 |
16 | 289294 | AXIN1 | rs214246 | [C/T] | 148/349/196 | 0.47 | 148/349/196 | 0.49 | 0.93 | 0.77 - 1.12 | 0.45 |
16 | 303385 | AXIN1 | rs12930863 | [C/T] | 20/175/490 | 0.16 | 20/175/490 | 0.16 | 1.05 | 0.81 - 1.36 | 0.70 |
16 | 313818 | AXIN1 | rs11646942 | [A/C] | 51/261/355 | 0.27 | 51/261/355 | 0.31 | 0.89 | 0.72 - 1.1 | 0.29 |
16 | 333343 | AXIN1 | rs395901 | [A/G] | 7/115/569 | 0.09 | 7/115/569 | 0.09 | 0.82 | 0.6 - 1.14 | 0.24 |
16 | 336265 | AXIN1 | rs1805105 | [A/G] | 67/310/284 | 0.34 | 67/310/284 | 0.31 | 1.19 | 0.97 - 1.47 | 0.10 |
16 | 68112382 | NFAT5 | rs12921716 | [A/G] | 6/113/575 | 0.09 | 6/113/575 | 0.08 | 0.95 | 0.68 - 1.32 | 0.75 |
16 | 68117197 | NFAT5 | rs4783720 | [C/T] | 22/184/488 | 0.16 | 22/184/488 | 0.15 | 1.10 | 0.85 - 1.43 | 0.47 |
16 | 68200854 | NFAT5 | rs17297207 | [G/A] | 3/69/612 | 0.05 | 3/69/612 | 0.07 | 0.66 | 0.44 - 0.98 | 0.04 |
16 | 68203623 | NFAT5 | rs11639947 | [T/C] | 22/183/467 | 0.17 | 22/183/467 | 0.21 | 0.80 | 0.63 - 1.02 | 0.07 |
16 | 68281721 | NFAT5 | rs1064825 | [A/G] | 0/74/619 | 0.05 | 0/74/619 | 0.06 | 0.84 | 0.55 - 1.28 | 0.42 |
16 | 68290961 | NFAT5 | rs7359336 | [G/A] | 128/329/227 | 0.43 | 128/329/227 | 0.41 | 1.04 | 0.86 - 1.26 | 0.69 |
17 | 42163544 | WNT3 | rs35937770 | [A/G] | 83/321/283 | 0.35 | 83/321/283 | 0.35 | 0.99 | 0.81 - 1.21 | 0.90 |
17 | 42188384 | WNT3 | rs35732828 | [A/C] | 19/200/466 | 0.17 | 19/200/466 | 0.17 | 1.05 | 0.81 - 1.35 | 0.71 |
17 | 42209035 | WNT3 | rs199520 | [G/A] | 38/237/419 | 0.23 | 38/237/419 | 0.22 | 1.04 | 0.83 - 1.3 | 0.75 |
17 | 42221887 | WNT3 | rs199496 | [A/G] | 5/117/569 | 0.09 | 5/117/569 | 0.07 | 1.11 | 0.78 - 1.58 | 0.56 |
17 | 42221965 | WNT3 | rs11658976 | [G/A] | 129/338/227 | 0.43 | 129/338/227 | 0.42 | 1.03 | 0.85 - 1.25 | 0.74 |
17 | 42223260 | WNT3 | rs11655598 | [G/C] | 46/249/387 | 0.25 | 46/249/387 | 0.29 | 0.94 | 0.76 - 1.16 | 0.57 |
17 | 42223353 | WNT3 | rs12452064 | [A/G] | 147/322/211 | 0.45 | 147/322/211 | 0.43 | 1.08 | 0.9 - 1.3 | 0.42 |
17 | 42224733 | WNT3 | rs10432043 | [T/C] | 86/301/284 | 0.35 | 86/301/284 | 0.33 | 1.07 | 0.88 - 1.31 | 0.50 |
17 | 42234514 | WNT3 | rs7207916 | [A/G] | 113/313/267 | 0.39 | 113/313/267 | 0.43 | 0.93 | 0.77 - 1.12 | 0.43 |
17 | 42243374 | WNT3 | rs11079737 | [A/G] | 54/268/338 | 0.28 | 54/268/338 | 0.27 | 1.12 | 0.91 - 1.38 | 0.30 |
17 | 42259048 | WNT3 | rs11079738 | [G/A] | 143/362/188 | 0.47 | 143/362/188 | 0.47 | 1.02 | 0.84 - 1.23 | 0.88 |
17 | 42261948 | WNT3 | rs8069437 | [T/C] | 35/225/433 | 0.21 | 35/225/433 | 0.23 | 0.85 | 0.68 - 1.07 | 0.16 |
19 | 51775092 | CALM3 | rs8103534 | [C/T] | 63/298/333 | 0.31 | 63/298/333 | 0.31 | 0.96 | 0.78 - 1.18 | 0.67 |
19 | 51781925 | CALM3 | rs4274528 | [T/C] | 7/144/542 | 0.11 | 7/144/542 | 0.12 | 1.17 | 0.87 - 1.57 | 0.31 |
19 | 51790267 | CALM3 | rs7260181 | [C/T] | 146/355/193 | 0.47 | 146/355/193 | 0.46 | 1.08 | 0.89 - 1.31 | 0.43 |
19 | 51798474 | CALM3 | rs4380146 | [G/T] | 69/284/327 | 0.31 | 69/284/327 | 0.32 | 1.03 | 0.84 - 1.26 | 0.76 |
19 | 51800325 | CALM3 | rs11671131 | [C/T] | 12/167/513 | 0.14 | 12/167/513 | 0.14 | 0.87 | 0.67 - 1.14 | 0.32 |
19 | 51804580 | CALM3 | rs710889 | [A/G] | 94/315/285 | 0.36 | 94/315/285 | 0.36 | 0.93 | 0.76 - 1.13 | 0.47 |
19 | 51804978 | CALM3 | rs10405893 | [A/G] | 5/153/535 | 0.12 | 5/153/535 | 0.11 | 1.25 | 0.92 - 1.69 | 0.16 |
19 | 51811750 | CALM3 | rs11083840 | [G/T] | 118/341/235 | 0.42 | 118/341/235 | 0.44 | 0.91 | 0.75 - 1.1 | 0.32 |
19 | 51811873 | CALM3 | rs11083841 | [G/A] | 26/181/457 | 0.18 | 26/181/457 | 0.16 | 1.15 | 0.9 - 1.47 | 0.26 |