Table 4 Blood parameter, treatment dose and variability (MSSD) of Period 1–2 vs. Period 3–4, C.E.R.A
C.E.R.A. | Period 1–2 | Period 3–4 | p-value |
|---|---|---|---|
(n = 19) | (n = 19) | ||
Hemoglobin, g/dl (mean, SD) | 11.2 (1.2) | 11.6 (0.7) | 0.16 |
Reticulocyte count, cells/μl (mean, SD) | 68367 (17794) | 78916 (20626) | 0.10 |
Ferritin, μg/l (mean, SD) | 444.4 (140.9) | 433.1 (105.3) | 0.78 |
Cumulated ESA dose, μg (mean, SD) | 950.3 (544.5) | 895 (657.7) | 0.79 |
Cumulated iron dose, μg (mean, SD) | 684.2 (285.3) | 712.5 (272.9) | 0.77 |
ST-MSSD Hb, g 2 /dl 2 (mean, SD) | 0.56 (0.67) | 0.52 (0.40) | 0.83 |
LT-MSSD Hb, g 2 /dl 2 (mean, SD) | 0.64 (0.51) | 1.25 (1.10) | 0.03 |
ST-MSSD Ret, cells 2 /μl 2 (mean, SD) | 35.8x108 (29.6x108) | 16.5x108 (14.4x108) | 0.01 |
LT-MSSD Ret, cells 2 /μl 2 (mean, SD) | 5.4x108 (7.3x108) | 12.1x108 (15.5x108) | 0.10 |
LT-MSSD ESA, μg 2 (mean, SD) | 10609 (16963) | 29043 (12641) | 0.25 |