Table 1 Clinical characteristics and plasma S100A12 levels in the development population
| Â | All (n = 550) | Died (n = 50) | Survived (n = 500) | Pvalue a |
|---|---|---|---|---|
Age (years) | 63.4 ± 12.1b | 69.9 ± 10.1 | 62.8 ± 12.1 | <0.001** |
Male/Female (n) | 355/195 | 32/18 | 323/177 | 0.933 |
Current smoker/nonsmoker (n) | 65/485 | 7/43 | 58/442 | 0.616 |
Duration of HD (years) | 9.7 ± 8.4 | 9.7 ± 8.8 | 9.7 ± 8.3 | 0.969 |
Systolic BP (mmHg) | 143.4 ± 26.0 | 143.4 ± 26.0 | 142.9 ± 22.0 | 0.878 |
Hemoglobin (g/dL) | 10.3 ± 1.1 | 10.4 ± 1.2 | 10.3 ± 1.1 | 0.589 |
White blood cells (/mm3) | 5729 ± 1816 | 5814 ± 1554 | 5720 ± 1841 | 0.728 |
Platelet (104/μL) | 16.8 ± 5.9 | 16.1 ± 6.0 | 16.8 ± 5.9 | 0.398 |
hs-CRP (mg/L) | 1.0 (0.4–3.0)c | 2.1 (0.8–6.3) | 0.9 (0.4–2.7) | <0.001** |
Creatinine (mg/dL) | 10.5 ± 2.6 | 9.6 ± 2.8 | 10.6 ± 2.6 | 0.010* |
Albumin (g/dL) | 3.7 ± 0.4 | 3.5 ± 0.4 | 3.7 ± 0.4 | <0.001** |
Sodium (mEq/L) | 139.5 ± 3.0 | 138.4 ± 3.0 | 139.6 ± 2.9 | 0.003** |
Potassium (mEq/L) | 4.6 ± 0.7 | 4.4 ± 0.8 | 4.6 ± 0.7 | 0.175 |
Adjusted calcium (mg/dL) | 9.3 ± 0.6 | 9.2 ± 0.6 | 9.3 ± 0.6 | 0.380 |
Phosphate (mg/dL) | 4.7 ± 1.1 | 4.5 ± 1.2 | 4.7 ± 1.1 | 0.283 |
Calcium (mg/dL) × Phosphate (mg/dL) | 41.5 ± 10.5 | 39.0 ± 10.4 | 41.8 ± 10.5 | 0.074 |
Total cholesterol (mg/dL) | 162.3 ± 45.8 | 158.4 ± 43.2 | 162.7 ± 46.1 | 0.534 |
DN/nonDN (n) | 202/348 | 22/28 | 180/320 | 0.263 |
History of CVD/no history of CVD (n) | 197/353 | 30/20 | 167/333 | <0.001** |
Plasma S100A12 levels (ng/mL) | 18.79 (11.70–30.37)c | 25.10 (16.21–47.64) | 17.93 (11.16–29.28) | 0.001** |