Table 3 Median biomarker levels [25-75% IQR], (range) when AKI is defined as a >50% increase in serum creatinine
| Â | AKI | no AKI | p-value |
|---|---|---|---|
Urine IL-18 (pg/mL) | Â | Â | Â |
   pre-op | 0 | 0 | 0.4274 |
[0–18.57] | [0–0] | ||
(0–1369) | (0–32.16) | ||
   post-op | 884.09 | 0 | 0.0449 |
[0–5024.4] | [0–42.73] | ||
|  | (0–5024.4) | (0–4915.6) | |
Urine NGAL (ng/mL) | Â | Â | Â |
   pre-op | 20.27 | 6.52 | 0.1848 |
[4.70-272.12] | [3.41-10.76] | ||
(0.97-8672.2) | (0.05-56.82) | ||
   post-op | 386.86 | 24.31 | 0.0039 |
[71.38-1611.48] | [9.97-45.20] | ||
(41.23-1824.6) | (1.69-5522.1) | ||
Urine IL-6 (pg/mL) | Â | Â | Â |
   pre-op | 6.82 | 6.34 | 0.1577 |
[4.28-50.11] | [1.59-9.36] | ||
(1.90-376.58) | (0–40.59) | ||
   post-op | 52.00 | 7.29 | 0.0532 |
[5.55-77.22] | [3.81-13.16] | ||
(20.61-84.04) | (0.48-130.34) | ||
Serum IL-6 (pg/mL) | Â | Â | Â |
   pre-op | 14.21 | 10.28 | 0.6693 |
[5.75-24.19] | [6.05-17.54] | ||
(3.33-67.14) | (1.21-60.18) | ||
   post-op | 44.76 | 18.75 | 0.1025 |
[17.54-133.67] | [9.38-38.71] | ||
(13–3020.6) | (4.23-171.77) | ||
Urine IL-8 (pg/mL) | Â | Â | Â |
   pre-op | 0 | 0 | 0.1881 |
[0–131.70] | [0–0] | ||
(0–200.1) | (0–143.2) | ||
   post-op | 14.30 | 0 | 0.0224 |
[0–143.00] | [0–0] | ||
(0–163.8) | (0–238.8) | ||
Serum IL-8 (pg/mL) | Â | Â | Â |
   pre-op | 12.36 | 6.53 | 0.6175 |
[3.50-30.51] | [0–36.35] | ||
(0–114.78) | (0–786.23) | ||
   post-op | 242.48 | 82.37 | 0.0463 |
[97.28-341.00] | [20.14-133.58] | ||
(41.53-1267.5) | (0–598.99) |