Table 5 Median biomarker levels (range) when AKI is defined as a >50% increase in cystatin C
| Â | AKI | no AKI | p-value |
|---|---|---|---|
Urine IL-18 (pg/mL) | Â | Â | Â |
   pre-op | 0 | 0 | 0.932 |
(0–18.57) | (0–1369.00) | ||
   post-op | 85.54 | 1.73 | 0.354 |
(0–5024.4) | (0–5024.4) | ||
Urine NGAL (ng/mL) | Â | Â | Â |
   pre-op | 7.41 | 7.24 | 0.712 |
(0.97-32.75) | (0.05-8672.2) | ||
   post-op | 386.86 | 24.98 | 0.0144 |
(33.76-5522.1) | (1.69-1655.2) | ||
Urine IL-6 (pg/mL) | Â | Â | Â |
   pre-op | 19.03 | 5.95 | 0.2236 |
(0–50.11) | (0–376.58) | ||
   post-op | 33.14 | 7.37 | 0.0171 |
(5.55-130.34) | (0.48-105.13) | ||
Serum IL-6 (pg/mL) | Â | Â | Â |
   pre-op | 16.03 | 8.92 | 0.8344 |
(3.33-24.19) | (1.21-67.14) | ||
   post-op | 17.54 | 20.26 | 0.6637 |
(7.26-3020.6) | (4.23-171.77) | ||
Urine IL-8 (pg/mL) | Â | Â | Â |
   pre-op | 0 | 0 | 0.6468 |
(0–131.70) | (0–200.10) | ||
   post-op | 14.30 | 0 | 0.0184 |
(0–238.8) | (0–106.30) | ||
Serum IL-8 (pg/mL) | Â | Â | Â |
   pre-op | 9.12 | 3.26 | >0.9999 |
(0–107.00) | (0–786.23) | ||
   post-op | 97.28 | 83.99 | 0.3318 |
(33.10-1267.50) | (0–598.99) |