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Table 4 Correlations between biomarkers and PWV and eGFR

From: Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease

 

eGFR

PWV

 

ρ

P-value

ρ

P-value

E-selectin

−0.441

<0.001

0.281

0.006

P-selectin

−0.272

<0.001

0.125

0.228

ICAM-1

−0.541

<0.001

0.193

0.061

VCAM-1

−0.264

<0.001

0.417

<0.001

sRAGE

−0.369

<0.001

0.052

0.615

ENRAGE

0.086

0.215

0.143

0.167

IL-8

−0.208

0.002

0.106

0.305

MCP-1

−0.203

0.003

0.069

0.505

MIP-1β

−0.130

0.061

0.185

0.073

C-reactive protein

−0.214

<0.001

0.272

<0.001

TNF-α

−0.323

<0.001

0.218

0.034

PAI-1

0.157

0.023

0.072

0.489

Adiponectin

−0.239

<0.001

.0245

0.017

Osteopontin

−0.602

<0.001

0.377

<0.001

Calcium

−0.312

0.001

−0.126

0.317

Phosphate

0.977

<0.001

0.261

0.037

Calcium × Phosphate

−0.329

0.001

0.207

0.101

Leptin

−0.384

<0.001

0.268

0.009

  1. eGFR estimated glomerular filtration rate, PWV pulse wave velocity, ICAM-1 intercellular adhesion molecule-1, VCAM-1 vascular cell adhesion molecule-1, sRAGE soluble receptor of advanced glycation end-products, ENRAGE extracellular newly identified receptor for advanced glycation end-products binding protein, MCP-1 monocyte chemoattractant protein 1, MIP-1β macrophage inflammatory protein-1 beta, TNF-α tumor necrosis factor alpha, PAI-1 plasminogen activator inhibitor-1. Spearman correlation coefficients (ρ) and associated P-values are given.
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BMC Nephrology

ISSN: 1471-2369

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