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Table 3 Longitudinal associations between anthropometric/ blood parameters and eGFR by sex

From: Body mass index and metabolic factors predict glomerular filtration rate and albuminuria over 20 years in a high-risk population

 

Previous parameters (over 20 years ago)

Previous parameters (10 to 20 years ago)

Previous parameters (5 to 10 years ago)

Current parameters (RENVOR)

 

Beta (95% CI)

 

Women

N

35

35

35

35

Follow-up [years], median (Q1, Q3)

24.7 (23.5, 25.2)

15.0 (14.1, 15.4)

7.5 (7.1, 7.9)

-

BMI [kg/m2]

0.47 (−0.75, 1.69)

0.02 (−0.82, 0.87)

−0.03 (−0.78, 0.72)

0.35 (−0.42, 1.11)

Systolic blood pressure [mmHg]

0.21 (−0.04, 0.47)

* 0.22 (0.03, 0.42)

0.14 (−0.10, 0.37)

-

Log(Glucose) [mmol/l]

−2.99 (−19.89, 13.91)

−4.30 (−30.30, 21.69)

10.43 (−13.69, 34.56)

-

Total cholesterol [mmol/l]

1.04 (−5.91, 8.00)

1.07 (−4.83, 6.96)

−2.31 (−8.43, 3.80)

−2.71 (−8.03, 2.61)

Log(Triglycerides) [mmol/l]

2.90 (−16.61, 22.41)

−2.17 (−11.50, 7.17)

2.50 (−8.43, 13.43)

−0.91 (−11.82, 9.99)

Log(Gamma-GT) [units/l]

4.00 (−6.60, 14.59)

−4.37 (−12.79, 4.05)

−2.85 (−9.51, 3.81)

* -4.41 (−8.81, −0.00)

 

Men

N

42

42

42

42

Follow-up [years], median (Q1, Q3)

24.3 (21.9, 25.3)

14.9 (14.1, 15.9)

7.4 (6.9, 8.1)

-

BMI [kg/m2]

* -0.99 (−1.75, −0.24)

* -0.78 (−1.39, −0.17)

* -1.05 (−1.62, −0.48)

* -0.79 (−1.40, −0.19)

Systolic blood pressure [mmHg]

0.05 (−0.11, 0.21)

−0.14 (−0.30, 0.02)

0.02 (−0.13, 0.16)

-

Log(Glucose) [mmol/l]

* -9.70 (−17.41, −1.99)

−2.63 (−10.27, 5.01)

−5.33 (−16.18, 5.52)

-

Total cholesterol [mmol/l]

−2.04 (−4.20, 0.11)

−1.28 (−3.76, 1.20)

−1.81 (−4.45, 0.82)

−0.76 (−3.32, 1.81)

Log(Triglycerides) [mmol/l]

−4.29 (−9.51, 0.93)

−0.81 (−5.30, 3.68)

−4.02 (−8.83, 0.80)

−3.48 (−9.39, 2.43)

Log(Gamma-GT) [units/l]

−2.13 (−6.24, 1.97)

−0.78 (−5.62, 4.05)

−1.07 (−5.12, 2.98)

0.67 (−3.13, 4.47)

  1. Models are adjusted for age.
  2. * Significant on alpha < = 0.05.