Association between family members of dialysis patients and chronic kidney disease: a multicenter study in China

BMC Nephrology

Table 3 Comparison of demographic and clinical characteristics between relatives of dialysis patients and controls

Variables	Relatives (n = 1062)	Controls (n = 2124)	P Value
Age (y)	44.0 ± 12.1	43.7 ± 12.3	0.61
Male (%)	401 (37.8)	802 (37.8)	1.0
Education (≥High School, %)	810 (76.3)	1393 (65.8)	<0.001
Hypertension (%)	278 (26.3)	721 (34.0)	<0.001
Diabetes (%)	109 (10.3)	162 (7.7)	0.02
Overweight (%)	588 (55.6)	1182 (55.7)	1.0
Nephrotoxic medications (%)	67 (6.4)	51 (2.4)	<0.001
Chronic respiratory tract infection (%)	178 (16.9)	300 (14.1)	0.05
Dyslipidemia (%)	480 (45.2)	673 (31.7)	<0.001
eGFR (mL/min/1.73 m²)	94.0 ± 16.9	92.4 ± 18.9	0.03
Low eGFR (%) <60 (mL/min/1.73 m²)	16 (1.5)	50 (2.4)	0.12
Albuminuria (%)	149 (14.4)	178 (8.4)	<0.001
CKD (%)	155 (14.6)	221 (10.5)	<0.01

Note: Data expressed as mean ± standard deviation or number (percentage); Overweight was defined as body mass index >24 kg/m²; Dyslipidemia was defined as present if total cholesterol was ≥ 5.72 mmol/L (220 mg/dL), or if low density lipoprotein was ≥ 3.64 mmol/L (140 mg/dL), or triglyceride was ≥ 1.70 mmol/L (150 mg/dL) or high density lipoprotein was < 0.91 mmol/L (35 mg/dL); Albuminuria was defined as urinary albumin-creatinine ratio ≥ 17 mg/g (1.9 mg/mmoL) for males and 25 mg/g (2.8 mg/mmoL) for females; CKD was defined as decreased kidney function (<60 mL/min/1.73 m²) or albuminuria.
Abbreviations: eGFR, estimated glomerular filtration rate; CKD, chronic kidney disease.

ISSN: 1471-2369