Table 2 Comparison of various parameters in glomerular filtration stages of chronic kidney disease in type 2 diabetes patients (n=182)
From: Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease
G1 | G2 | G3 | G4 | Total | Jonckheere-Terpstra | |
|---|---|---|---|---|---|---|
Number (male/female) | 37 (21 / 16) | 99 (37 / 62) | 41 (12 / 29) | 5 (1 / 4) | 182 (71 / 111) | 0.009** |
Age (years) | 50.0±15.5 | 60.7±10.8 | 70.2±11.7 | 73.8±7.8 | 60.4±14.4 | 6.43×10-10** |
BMI (kg/m2) | 27.0±6.9 | 25.5±4.8 | 24.7±4.0 | 25.9±1.7 | 25.6±5.1 | 0.242 |
SBP (mmHg) | 128.9±14.7 | 129.7±15.4 | 129.6±18.3 | 128.2±18.4 | 129.5±15.9 | 0.939 |
DBP (mmHg) | 77.7±10.8 | 74.5±10.9 | 73.1±12.9 | 67.4±9.8 | 74.7±11.4 | 0.031* |
PG (mmol/L) | 9.6±4.2 | 8.6±3.1 | 8.8±3.1 | 8.6±3.1 | 8.9±3.3 | 0.113 |
HbA1c (%) | 7.90±1.54 | 7.25±1.01 | 7.13±0.78 | 7.04±0.88 | 7.35±1.12 | 0.029* |
HbA1c (mmol/mol) | 65.3±16.0 | 58.5±10.5 | 57.3±8.1 | 73.1±9.1 | 76.4±11.6 | 0.029* |
ACR (mg/gCr) | 19.6±27.7 | 130.6±344.4 | 421.4±1191 | 702.1±603.0 | 196.6±655.0 | 0.005** |
Cr (μmol/L) | 49.5±8.8 | 66.3±11.5 | 94.6±23.0 | 245.8±114.9 | 74.3±39.8 | 3.45×10-21** |
UN (mmol/L) | 4.7±1.6 | 5.7±1.6 | 20.6±7.4 | 15.7±2.1 | 6.1±2.5 | 1.60×10-9** |
eGFR (mL/s) | 1.76±0.26 | 1.25±0.14 | 0.85±0.13 | 0.33±0.10 | 1.24±0.37 | 8.80×10-30** |
Osmotic pressure (mmol/kg) | 299.3±4.0 | 301.2±4.3 | 303.0±4.2 | 312.9±1.2 | 301.6±4.8 | 4.78×10-6** |
T-Cho (mmol/L) | 4.77±0.81 | 4.93±0.88 | 4.80±1.30 | 5.05±0.90 | 4.87±0.97 | 0.736 |
TG (mmol/L) | 1.51±0.74 | 1.51±0.77 | 1.68±0.91 | 2.19±1.16 | 1.56±0.81 | 0.391 |
HDL-C (mmol/L) | 1.48±0.36 | 1.61±0.54 | 1.53±0.45 | 1.27±0.06 | 1.56±0.49 | 0.776 |
LDL-C (mmol/L) | 2.67±0.70 | 2.79±0.68 | 2.73±0.80 | 3.09±0.99 | 2.75±0.72 | 0.753 |
Log10Gal-9 (pg/mL) | 1.89±0.41 | 1.94±0.42 | 2.02±0.43 | 2.27±0.32 | 1.96±0.42 | 0.012* |