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Table 3 Comparison of various parameters in albuminuria stages of chronic kidney disease in type 2 diabetes patients (n=182)

From: Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease

 

A1

A2

A3

Total

Jonckheere-Terpstra

Number (male/female)

108 (46 / 62)

47 (17 / 30)

27 (8 / 19)

182 (71 / 111)

0.075

Age (years)

60.0±14.0

63.5±13.5

62.0±12.7

60.4±14.4

0.199

BMI (kg/m2)

25.3±1.5

26.2±6.2

27.3±5.1

25.6±5.1

0.227

SBP (mmHg)

128.8±13.3

132.7±19.7

137.0±20.0

129.5±15.9

0.071

DBP (mmHg)

75.1±9.9

72.7±13.1

78.3±16.6

74.7±11.4

0.982

PG (mmol/L)

8.5±3.0

9.6±3.9

9.1±2.7

8.9±3.3

0.170

HbA1c (%)

7.27±0.87

7.51±1.35

7.61±1.41

7.35±1.12

0.611

HbA1c (mmol/mol)

75.5±9.0

78.0±14.0

79.0±14.6

76.3±11.6

0.611

ACR (mg/gCr)

11.2±6.2

110.7±83.4

1474±1444

196.6±655.0

5.06×10-23**

Cr (μmol/L)

69.0±40.7

73.4±19.4

114.9±53.9

74.3±39.8

2.44×10-4**

UN (mmol/L)

5.8±2.1

6.5±1.9

9.1±4.1

6.1±2.5

2.04×10-4**

eGFR (mL/s)

1.29±0.34

1.17±0.30

0.86±0.37

1.24±0.37

2.55×10-4**

Osmotic pressure (mmol/kg)

301.0±4.0

300.9±4.7

306.7±4.8

301.6±4.8

0.013*

T-Cho (mmol/L)

4.85±0.92

5.00±1.17

4.98±0.94

4.87±0.97

0.688

TG (mmol/L)

1.44±0.71

1.75±0.82

1.72±0.84

1.56±0.81

0.051

HDL-C (mmol/L)

1.57±0.49

1.52±0.51

1.56±0.54

1.56±0.49

0.413

LDL-C (mmol/L)

2.77±0.62

2.90±0.85

2.78±0.77

2.75±0.72

0.890

Log10Gal-9 (pg/mL)

1.97±0.43

1.90±0.45

1.98±0.30

1.96±0.42

0.374

  1. BMI, body mass index; SBP, Systolic Blood Pressure; DPB, Diastolic Blood Pressure; PG, Plasma glucose; ACR, albumin / creatinine ratio; Cr, serum creatinine; UN, serum urea nitrogen; eGFR, estimated glomerular filtration ratio; T-Cho, Total cholesterol; TG, Triglyceride; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; Log10Gal-9, Log10galectin-9 (pg/mL). *, p < 0.05; **, p < 0.01.