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Table 2 Kidney function by glycemic status, with estimation of GFR by the MDRD Study equation and the CKD-EPI equation

From: Prevalence of chronic kidney disease across levels of glycemia among adults in Pudong New Area, Shanghai, China

Characteristic

Glycemic status

P

Diagnosed diabetes

Undiagnosed diabetes

Prediabetes

Normoglyciemia

 

n

Prevalence (95% CI)

n

Prevalence (95% CI)

n

Prevalence (95% CI)

n

Prevalence (95% CI)

 

Albuminuria (%)

100

28.9 (24.1-33.7)

77

28.1 (22.8-33.5)

176

12.9 (11.2-14.7)

308

8.7 (7.8-9.6)

<0.001

Microalbuminuria (%)

81

23.4 (18.9-27.9)

71

26.0 (20.8-31.2)

162

12 (10.3-13.8)

296

8.4 (7.5-9.3)

<0.001

Macroalbuminuria (%)

19

5.5 (3.1-7.9)

6

2.2 (0.5-4.0)

14

1.0 (0.5-1.6)

12

0.3 (0.2-0.5)

<0.001

MDRD Study–estimated

         

Decreased kidney function (%)

12

3.5 (1.5-5.4)

5

1.8 (0.2,3.4)

35

2.6 (1.7,3.4)

31

0.9 (0.6,1.2)

<0.001

  CKD (%)

107

30.9 (26.0-35.8)

78

28.5 (23.1-33.8)

192

14.1 (12.3-16.0)

326

9.2 (8.2-10.1)

<0.001

  CKD Stage 1

73

6.1 (3.5-8.6)

63

3.7 (1.4-5.9)

113

3.2 (2.3-4.2)

230

1.7 (1.3-2.2)

0.002

  CKD Stage 2

21

6.1 (3.5-8.6)

10

3.7 (1.4-5.9)

44

3.2 (2.3-4.2)

62

1.7 (1.3-2.2)

  CKD Stage 3

8

2.3 (0.7-3.9)

4

1.5 (0.0-2.9)

33

2.4 (1.6-3.3)

24

0.7 (0.4-0.9)

  CKD Stage 4/5

2

0.6 (0.2,1.4)

0

0.0 (0.0-0.0)

0

0.0 (0.0-0.0)

2

0.1 (0.0-0.1)

CKD-EPI–Estimated

         

Decreased kidney function (%)

21

6.1 (3.5-8.6)

8

2.9 (0.9-4.9)

56

4.1 (3.1-5.2)

58

1.6 (1.2-2.1)

<0.001

  CKD (%)

114

33.6 (28.5-38.5)

80

29.2 (23.8-34.6)

204

15.2 (13.4-17.2)

342

9.8 (8.8-10.8)

<0.001

  CKD Stage 1

63

18.2 (14.1-22.2)

52

19.0 (14.3-23.7)

96

7.1 (5.7-8.4)

208

5.9 (5.1-6.6)

<0.001

  CKD Stage 2

37

10.7 (7.4-14.0)

25

9.1 (5.7-12.6)

80

5.9 (4.6-7.1)

100

2.8 (2.3-3.4)

  CKD Stage 3

13

3.8 (1.7-5.8)

3

1.1 (0.2-2.3)

28

2.1 (1.3-2.8)

34

1.0 (0.6-1.3)

  CKD Stage 4/5

1

0.3 (0.2-0.9)

0

0.0 (0.0-0.0)

0

0.0 (0.0-0.0)

0

0.0 (0.0-0.0)

  1. Data presented as n, percentage (CI, confidence interval) for categorical variables. P value for χ 2 test (categorical variables).
  2. Albuminuria was defined as a urinary albumin-to-creatinine ratio (ACR) >30 mg/g creatinine; Microalbuminuria and macroalbuminuria were defined as a ACR between 30 and 299 mg/g and 300 mg/g or greater, respectively. CKD was defined as estimated glomerular filtration rate(eGFR) < 60 mL/min/1.73 m2 or albuminuria.
  3. Abbreviations: CKD Chronic kidney disease, CKD-EPI Chronic kidney disease epidemiology collaboration, MDRD Modification of diet in renal disease.