Table 2 Comparison of fluid overloaded and normohydrated patients from center 1
Patient characteristic | Fluid overloaded (n = 56) | Normohydrated (n = 70) | P-value |
|---|---|---|---|
Sex [male] | 68% | 54% | 0.137 |
Age [years] | 61.1 ± 17.3 | 56.4 ± 17.8 | 0.110 |
Vascular access [AVF] | 76% | 87% | 0.102 |
BMI [kg/m2] | 23.1 ± 4.4 | 26.4 ± 5.7 | 0.001 |
Weight pre-HD [kg] | 69.6 ± 16.6 | 75.5 ± 18.2 | 0.076 |
Weight post-HD [kg] | 68.3 ± 16.5 | 73.9 ± 17.9 | 0.092 |
UF [L] | 1.3 ± 1.0 | 1.6 ± 1.1 | 0.144 |
FO pre-HD [L] | 4.4 ± 1.5 | 1.0 ± 1.4 | <0.001 |
FO pre-HD [% ECW] | 22.9 ± 4.8 | 5.8 ± 7.7 | <0.001 |
FO post-HD [% ECW] | 14.9 ± 7.9 | - 3.0 ± 9.1 | <0.001 |
ECW pre-HD [L] | 18.8 ± 4.0 | 17.8 ± 5.3 | 0.290 |
No. of antihypertensives | 3.0 ± 1.7 | 2.8 ± 1.7 | 0.700 |
Systolic BP pre-HD [mmHg] | 137.7 ± 23.3 | 134.6 ± 18.8 | 0.413 |
Diastolic BP pre-HD [mmHg] | 72.9 ± 15.5 | 73.5 ± 14.8 | 0.829 |
Protein [g/l] | 64.9 ± 5.2 | 66.8 ± 5.3 | 0.056 |
Albumin [g/l] | 36.4 ± 3.8 | 38.5 ± 2.9 | 0.001 |
C-reactive protein [mg/dl] | 1.0 (0.3 – 2.3) | 0.5 (0.2 – 1.6) | 0.129 |
Hemoglobin [g/dl] | 10.2 ± 1.1 | 10.3 ± 1.2 | 0.491 |
Fibrinogen [mg/dl] | 389.2 ± 125.6 | 418.3 ± 129.5 | 0.221 |
D-Dimer [μg/ml] | 1.2 (0.6 – 2.1) | 0.7 (0.3 – 1.7) | 0.021 |
Troponin T [ng/ml] | 0.07 (0.05 – 0.17) | 0.05 (0.03 – 0.08) | 0.020 |
NT-proBNP [pg/ml] | 10436.5 (4239.3 – 35000) | 4485.0 (1956.7 – 11979.5) | 0.001 |
Serum amyloid A [mg/l] | 14.5 (6.5 – 34.2) | 7.6 (5.2 – 25.1) | 0.149 |
Kt/V | 1.5 ± 0.4 | 1.5 ± 0.3 | 0.596 |
Charlson comborbidity index | 4.96 ± 2.27 | 4.06 ± 2.04 | 0.024 |