Table 1 Baseline and intraoperative characteristics of the liver transplantation cohort stratified by time from AKI to RRT or serum creatinine peak
From: Impact of acute kidney injury exposure period among liver transplantation patients
Time from AKI onset to RRT or SCr peak | ||||
|---|---|---|---|---|
Less than a week (N = 221) | A week or more (N = 94) | Totals (N=315) | p value | |
Age (years) | 53 (46 – 60) | 53 (45 – 58) | 53 (46 – 60) | 0.502 |
Weight (kg) | 72 (62 – 81) | 72 (60 – 82) | 72 (62 – 82) | 0.538 |
Height (cm) | 169 (162 – 174) | 168 (160 – 175) | 169 (162 – 174) | 0.446 |
Men | 148 (67%) | 59 (63%) | 207 (66%) | 0.472 |
Diabetes mellitus | 42 (19%) | 23 (24%) | 65 (21%) | 0.273 |
Hypertension | 16 (7%) | 8 (8%) | 24 (8%) | 0.697 |
Smoking habit | 10 (4%) | 1 (1%) | 11 (4%) | 0.126 |
eGFR (MDRD) | 92 (74 – 113) | 96 (76 – 110) | 93 (74 – 112) | 0.508 |
Previous serum creatinine (mg/dl) | 0.8 (0.7 – 1.0) | 0.8 (0.7 – 1.0) | 0.8 (0.7 – 1.0) | 0.385 |
Serum albumin (mg/dl) | 3.1 (2.7 – 3.4) | 3.1 (2.8 – 3.5) | 3.1 (2.7 – 3.5) | 0.100 |
Total bilirubin (mg/dl) | 2.6 (1.7 – 4.1) | 2.4 (1.6 – 3.8) | 2.6 (1.7 – 4.0) | 0.419 |
Main Indication for LT | ||||
Hepatitis B | 22 (10%) | 12 (13%) | 34 (11%) | 0.462 |
Hepatitis C | 110 (50%) | 48 (51%) | 158 (50%) | 0.834 |
Alcoholic cirrhosis | 55 (25%) | 21 (22%) | 76 (24%) | 0.629 |
Acute liver failure | 6 (19%) | 3 (3%) | 9 (3%) | 0.816 |
Liver malignancy | 48 (22%) | 27 (29%) | 75 (24%) | 0.182 |
Other cirrhotic | 43 (19%) | 18 (19%) | 61 (19%) | 0.950 |
MELD score | 14 (10 – 18) | 12 (9 – 15) | 13 (9 – 17) | 0.067 |
Child-Pugh stage | 0.075 | |||
A | 32 (14%) | 22 (23%) | 54 (17%) | |
B | 110 (50%) | 48 (51%) | 158 (50%) | |
C | 79 (36%) | 24 (26%) | 103 (33%) | |
Deceased liver donor | 126 (57%) | 55 (58%) | 181 (58%) | 0.806 |
Piggyback technique | 214 (97%) | 92 (98%) | 306 (97%) | 0.612 |
Total ischemia time (h) | 6.6 (2.4 – 10) | 6.9 (2.5 – 10) | 6.7 (2.4 – 10) | 0.716 |
Surgical time (h) | 7.8 (7 – 8.5) | 7.5 (7 – 8.5) | 7.6 (7 – 8.5) | 0.405 |
Blood products (units) | 4 (2 – 9) | 3 (1 – 5) | 4 (2 – 8) | 0.027 |
Aprotinin | 65 (29%) | 18 (19%) | 83 (26%) | 0.059 |
Intraoperative pressor | 20 (9%) | 5 (5%) | 25 (8%) | 0.262 |
APACHE II score | 15 (13 – 19) | 16 (14 – 19) | 16 (13 – 19) | 0.243 |