From: Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB
Serum indoxyl sulfate (mg/dl) | |
---|---|
Animal study 1 | |
DN | 0.10±0.01 |
DN+IS | 0.94±0.13**### |
DH | 0.06±0.01 |
DH+IS | 1.89±0.26**### |
Animal study 2 | |
Normal | 0.08±0.007 |
CKD | 0.52 ± 0.16* |
CKD+AST-120 | 0.12±0.02# |