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Table 2 Baseline anthropometrical data and treatments at enrolment

From: Observational multicenter study to evaluate the prevalence and prognosis of subclinical atheromatosis in a Spanish chronic kidney disease cohort: baseline data from the NEFRONA study

 

Controls

CKD

CKD stage 3

CKD stages 4-5

CKD stage 5D

p value

p value

n =559

n =2445

n =937

n =820

n =688

CKD vs controls

Between CKD groups

Anthropometrical data

       

SBP (mmHg)

133.2 ± 17.7

142.9 ± 22.0

142.9 ± 20.2

146.7 ± 22.1

138.4 ± 23.4

<0.001

<0.001

DBP (mmHg)

80.0 ± 9.7

81.3 ± 11.9

81.6 ± 10.2

82.2 ± 11.4

80.0 ± 14.2

0.010

0.005

Pulse pressure (mmHg)

53.2 ± 13.0

61.6 ± 18.3

61.3 ± 16.9

64.5 ± 19.4

58.4 ± 18.3

<0.001

<0.001

BMI (Kg/m2)

28.1 ± 4.5

28.3 ± 5.2

29.2 ± 4.9

28.8 ± 5.5

26.5 ± 4.9

NS

<0.001

Abdominal obesity (%)*

47.8

49.6

58.9

49.3

34.4a

NS

<0.001

Pharmacological treatments

       

Antihypertensive (%)

34.5

88.1

91.8

95.6

74.3

<0.001

<0.001

Hypolipidemic (%)

27.4

64.4

67.6

70.7

52.5

<0.001

<0.001

Antidiabetic (%)

9.5

21.9

23.5

25.2

15.8

<0.001

<0.001

Antiaggregation (%)

5.9

24.8

23.6

23.8

27.6

<0.001

NS

Anticoagulation (%)

0.5

3.1

3.2

3.0

3.2

<0.001

NS

Vitamin D (%)

N/A

38.7

18.0

50.4

53.1

N/A

<0.001

Of which active (%)

N/A

32.1

12.0

42.8

46.9

N/A

<0.001

Of wich native (%)

N/A

10.2

7.0

13.6

10.6

N/A

<0.001

Phosphate binders (%)

N/A

35.7

5.7

31.1

82.0

N/A

<0.001

Non-calcium based (%)

N/A

22.2

1.0

14.7

60.1

N/A

<0.001

Calcium based (%)

N/A

21.1

4.9

20.4

43.8

N/A

<0.001

ESA (%)

N/A

35.6

5.7

32.2

80.4

N/A

<0.001

Intravenous iron (%)

N/A

18.7

1.7

8.2

54.5

N/A

<0.001

  1. Data expressed as percentage or mean value ± standard deviation. *Abdominal obesity defined as waist circumference >88 cm in women and >102 cm in men. aWaist circumference was not measured in peritoneal dialysis patients. Abbreviations: CKD chronic kidney disease, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, ESA erythropoiesis stimulating agents, N/A not assessed, NS not significant.