Variables | ADPKD | Non-ADPKD | P-value |
---|---|---|---|
(n = 6,749) | (n = 506,023) | ||
Gender | Â | Â | 0.426 |
 Male | 3,551 (52.6) | 268,709 (53.1) |  |
 Female | 3,198 (47.4) | 237,314 (46.9) |  |
Race | Â | Â | <0.001 |
 AA | 848 (12.6) | 123,256 (24.4) |  |
 Non-AA | 5,901 (87.4) | 382,767 (75.6) |  |
Mean age at start of dialysis (yr) | 65.30 | 70.20 | < 0.001 |
(95% CI 65.01-65.64) | (95% CI 70.21-70.28) | ||
Dialysis modality | Â | Â | <0.001 |
 Hemodialysis | 4,636 (79.4) | 412,185 (92.4) |  |
 Peritoneal dialysis | 1,206 (20.6) | 34,163 (7.7) |  |
Receipt of kidney transplant | 1,784 (26.4) | 24,743 (4.9) | <0.001 |
CHF | 1,002 (14.9) | 197,017 (39.6) | <0.001 |
Atherosclerotic heart disease | 1,144 (17.0) | 152,623 (30.7) | <0.001 |
Cerebrovascular disease (CVA, TIA) | 541 (8.0) | 59,859 (12.0) | <0.001 |
Peripheral vascular disease | 452 (6.7) | 91,337 (18.4) | <0.001 |
Hypertension | 5,682 (84.4) | 405,168 (81.4) | <0.001 |
Diabetes mellitus | 480 (7.1) | 212,998 (42.8) | <0.001 |
COPD | 470 (7.0) | 55,199 (11.1) | <0.001 |
Tobacco use | 426 (6.3) | 23,207 (4.7) | <0.001 |
Alcohol dependence | 43 (0.6) | 4,862 (1.0) | 0.005 |
Mean hemoglobin (g/dL) | 10.81 | 10.16 | <0.001 |
(95% CI 10.75-10.87) | (95% CI 10.16-10.17) | ||
Mean serum albumin (g/dL) | 3.66 | 3.13 | <0.001 |
(95% CI 3.63-3.69) | (95% CI 3.13-3.14) | ||
Mean total cholesterol (mg/dL) | 159.50 | 151.16 | <0.001 |
(95% CI 155.86-163.14) | (95% CI 150.68-151.64) | ||
Mean low density lipoprotein (mg/dL) | 92.61 | 87.41 | 0.017 |
(95% CI 88.39-96.83) | (95% CI 86.85-87.96) | ||
Mean body mass index (kg/m2) | 27.10 | 28.34 | <0.001 |
(95% CI 26.83-27.37) | (95% CI 28.30-28.37) |