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Table 1 Baseline characteristics according to randomization in a randomized, placebo-controlled, double-blinded study of 50 dialysis patients

From: Cardiovascular effects of cholecalciferol treatment in dialysis patients – a randomized controlled trial

 

Placebo

Vitamin-D3

P value

Age (years)

67 ± 13

68 ± 9

0.794

Body mass index (kg/m2)

23.8 ± 4.4

24.0 ± 4.5

0.856

Male sex, n (%)

15 (60)

17 (68)

0.556

Smokers, n (%)

   

  Current

5 (20)

1(4)

0.220

  Former

5 (20)

6 (24)

  Never

15 (60)

18 (72)

Type 1 diabetes, n (%)

4 (16)

2 (8)

0.384

Type 2 diabetes, n (%)

5 (20)

2 (8)

0.221

HD, n (%) A

24 (96)

19 (76)

0.042

  Dialysis sessions pr. week for HD patients

3.2 ± 0.6

3.2 ± 0.6

0.817

Medication, n (%)

   

  ACEi/ARBs

17 (68)

17 (68)

0.914

  Calcium channel blockers

7 (28)

13 (54)

0.083

  Beta blockers

11 (44)

15 (60)

0.285

  Loop diuretics

11 (44)

12 (40)

0.777

  Minoxidil

5 (20)

6 (24)

0.733

  Alfa-blockers

2 (8)

1 (4)

0.552

  Alfacalcidol

12 (48)

15 (60)

0.393

  Paricalcitol

1 (4)

1 (4)

1.000

  Cinecalcet

2 (8)

2 (8)

1.000

  Phosphate binder

17 (68)

20 (80)

0.333

  Lanthanum

3 (12)

4 (16)

0.684

  Sevelamer

10 (40)

14 (56)

0.258

  Calcium-containingB

15 (60)

17 (68)

0.254

  Erythropoetin analogue

24 (96)

21 (84)

0.157

  P-BNP (pmol/L)

81 (24;186)

61 (26;378)

0.600

  P-25(OH) D (nmol/L)

28 (20;69)

28 (20;48)

0.614

  1. Values are mean ± SD, n with percentage in brackets or medians with 25 and 75 percentiles in brackets. ACEi: Angiotensin converting enzyme inhibitors, ARB: Angiotensin receptor blocker. BNP: Brain natriuretic peptide, 25(OH): 25-hydroxy-vitamin D AOne subject changed from peritoneal dialysis to haemodialysis (HD) after two months and was placed in HD. BUnikalk or Osvaren.