Cardiovascular effects of cholecalciferol treatment in dialysis patients – a randomized controlled trial

BMC Nephrology

Table 3 Effect of 6 months cholecalciferol treatment 24 hour blood pressure (24-h BP) in a randomized, placebo-controlled study of 50 patients on dialysis

	Baseline	6 months	P value (difference in response)
24-h SBP (mmHg)
Placebo	136 ± 22	127 ± 23^†	0.511
Cholecalciferol	135 ± 18	130 ± 14	0.511
24-h DBP (mmHg)
Placebo	73 ± 10	69 ± 10	0.451
Cholecalciferol	73 ± 9	71 ± 8	0.451
24-h heart rate (bpm)
Placeb	74 ± 8	74 ± 7	0.464
Cholecalciferol	70 ± 9	71 ± 8	0.464
24-h daytime SBP (mmHg)
Placebo	138 ± 22	130 ± 22^†	0.504
Cholecalciferol	137 ± 18	133 ± 15	0.504
24-h daytime DBP (mmHg)
Placebo	75 ± 11	71 ± 11	0.519
Cholecalciferol	74 ± 9	72 ± 8	0.519
24-h daytime heart rate (bpm)
Placebo	75 ± 8	76 ± 8	0.586
Cholecalciferol	71 ± 9	73 ± 9	0.586
24-h nighttime SBP (mmHg)
Placebo	131 ± 26	121 ± 27^†	0.498
Cholecalciferol	129 ± 19	125 ± 17	0.498
24-h nighttime DBP (mmHg)
Placebo	69 ± 11	65 ± 11^†	0.361
Cholecalciferol	69 ± 9	68 ± 11	0.361
24-h nighttime heart rate (bpm)
Placebo	70 ± 8	70 ± ± 6	0.270
Cholecalciferol	67 ± 9	69 ± ± 9	0.270

Values are means ± SD. P values represent the probability of a difference in response to treatment between groups. Statistics are performed with t-test. Statistical significant difference from baseline compared with paired t-test. Statistical significant difference from baseline: ^† = p < 0.05.

ISSN: 1471-2369