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Table 7 Changes in antihypertensive mediation in a randomized, placebo-controlled study investigating the effects of cholecalciferol supplementation for 6 months in 50 patients on dialysis

From: Cardiovascular effects of cholecalciferol treatment in dialysis patients – a randomized controlled trial

Changes from baseline

ACE-inhibitor

AT2-antagonist

Calcium-antagonist

Beta-blockerA

Fourosemide

Minoxidil

Alfa-blocker

Moxonidine

Placebo

        

  Increased dose (n)

6

4

4

9

6

4

0

0

  Same dose (n)

18

19

19

14

15

16

25

25

  Reduced dose (n)

1

2

2

2

4

5

0

0

Cholecalciferol

        

  Increased dose (n)

3

5

3

4

7

4

2

1

  Same dose (n)

16

19

18

18

14

18

23

22

  Reduced dose (n)

6

1

4

3

4

3

0

2

  1. ACE: Angiotensin converting enzyme, AT2: Angiotensin 2. A1 patient in placebo and 1 patient in cholecalciferol group had metroprolol substituted with carvedilol in equivalent doses and is reported as given same dose beta-blocker.