Table 4 Use of antihypertensive medication by class of drugs among CKD patients with hypertension according to level of UACR
Anti-hypertensive medications | Overall, n (%, 95% CIs) | UACR, mg/mmol, n (%, 95% CIs) | ||
|---|---|---|---|---|
<3.0 | ≥3.0 | ≥3.0 and diabetes | ||
n = 267 | N = 56 | N = 211 | N = 107‡ | |
Antihypertensive medications, mean ± SD | 1.4 ± 0.8 | 1.4 ± 0.7 | 1.4 ± 0.8 | 1.5 ± 0.9 |
ACEI/ARB only | 26 (9.7, 6.5 – 13.9) | 7 (12.5, 5.2 – 24.1) | 19 (9.0, 5.5 – 13.7) | 10 (9.3, 4.6 – 16.5) |
ACEI/ARB only or in combination with others | 45 (16.9, 12.6 – 21.9) | 12 (21.4, 11.6 – 34.4) | 33 (15.6, 11–21.3) | 20 (18.7, 11.8 – 27.4) |
Beta blockers only | 43 (16.1, 11.9 – 21.1) | 9 (16.1, 7.6 – 28.3) | 34 (16.1, 11.4 – 21.8) | 13 (12.1, 6.6 – 19.9) |
Beta blockers only or in combination with others | 64 (24.0, 19.0 – 29.6) | 15 (26.8, 15.8 – 40.3) | 49 (23.2, 17.7 – 29.5) | 22 (20.6, 13.4 – 29.5) |
Calcium channel blockers only | 18 (6.7, 4.0 – 10.4) | 4 (7.1, 2.0 – 17.3) | 14 (6.6, 3.7 – 10.9) | 10 (9.3, 4.6 – 16.5) |
Calcium channel blockers only or in combination with others | 40 (15.0, 10.9 – 19.8) | 9 (16.1, 7.6 – 28.3) | 31 (14.7, 10.2 – 20.2) | 21 (19.6, 12.6 – 28.4) |
Diuretics only | 3 (1.1, 0.2 – 3.2) | 2 (3.6, 0.4 – 12.3) | 1 (0.5, 0.0 – 2.6) | 1 (0.9, 0.0 – 5.1) |
Diuretics only or in combination with others | 19 (7.1, 4.3 – 10.9) | 6 (10.7, 4–21.9) | 13 (6.2, 3.3 – 10.3) | 12 (11.2, 5.9 – 18.8) |
Any combinations† | 36 (13.5, 9.6 – 18.2) | 10 (17.9, 8.9 – 30.4) | 26 (12.3, 8.2 – 17.5) | 18 (16.8, 10.3 – 25.3) |