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Table 1 General characteristics of Han:SPRD rats (12 weeks old)

From: p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels

 

Males

 

Females

 
 

Control

Cystic

Control

Cystic

 

(n = 9)

(n = 12)

(n = 7)

(n = 11)

Body wt (gms)

385 ± 8

356 ± 7

253 ± 4†

242 ± 4†

LKW (gms)

1.47 ± 0.05

4.19 ± 0.13*

0.86 ± 0.03†

1.89 ± 0.04*†

LKW/100 gms BW

0.38 ± 0.01

1.18 ± 0.03*

0.34 ± 0.01

0.76 ± 0.01*†

  1. Values are means ± SEM. LKW, left kidney weight; BW, body weight. * p < 0.01 vs. respective noncystic control; † p < 0.01, female vs. respective male group
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BMC Nephrology

ISSN: 1471-2369

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