Analgesics use and ESRD in younger age: a case-control study

BMC Nephrology

Table 5 Adjusted relative risk of ESRD by increasing cumulative lifetime dose of analgesic use (all analgesics together).

Grams	Cases	Controls	OR (95% CI)
Low use	546	2030	1.00 (referent)
-500	278	1365	0.75 (0.64–0.88)
501–1000	41	133	1.10 (0.77–1.59)
1001–1500	10	47	0.76 (0.38–1.52)
1501–2000	6	19	1.03 (0.40–2.62)
2001–2500	4	9	1.50 (0.48–4.74)
2501–3000	3	8	1.35 (0.37–4.94)
3001 +	19	11	6.02 (2.83–12.81)

Categorical modeling for dose-response analyses. Odds ratios and 95% confidence intervals. Analysis based on index date 3 (5 years before start of dialysis), adjusted for age, sex, country. ORs were not calculated if the frequency in any group was less than 10 per cell: no data (n.d.) in the table. Standard reference group of low use is defined as exposure to less than one tablet or unit dose of any phenacetin-free analgesic compound per month across all 12-months periods in the observed lifetime.

ISSN: 1471-2369