Fig. 4

Effects of IMD on markers of endoplasmic reticulum stress (ERS) in IRI rats. a Representative protein expression of GRP78, CHOP, caspase-12, and β-actin as a control; Quantitative analysis of (b) GRP78, (c) CHOP, and (d) caspase-12 by Western blots. e The mRNA expression levels of GRP78, CHOP and caspase-12 were determined by real time-PCR. Data in bar graphs are means ± SD, n = 8. * P < 0.05, **P < 0.01 vs. sham group; # P < 0.05, ## P < 0.01 vs. IRI group, respectively