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Fig. 5 | BMC Nephrology

Fig. 5

From: Cells of renin lineage express hypoxia inducible factor 2α following experimental ureteral obstruction

Fig. 5

Nuclear translocation of HIF-2α in JG and afferent arteriole in UUO. Red fluorescent protein (red) staining identified CoRL, HIF-2α (green) staining was used to detect hypoxia-activated cells. Nuclei are labeled with DAPI (blue). In the sham kidney cortex, there was (a) a cytoplasmic HIF-2α staining in JG cells (inset shows single panel colors, arrowheads indicates the same cell). In UUO kidney, there was an accumulation of HIF-2α staining in the nuclei in afferent arterioles and JG (insets show single panel colors, arrowheads indicates the same cell) on (b) day 3, (c) day 7, (d) day 14 following kidney injury

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BMC Nephrology

ISSN: 1471-2369

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