Efficacy of the Essential Amino Acids and Keto-Analogues on the CKD progression rate in real practice in Russia - city nephrology registry data for outpatient clinic

Table 4 Reducing effect of EAA/KA on GFR slope decrease: the results of uni-variate analysis, categorical variable comparison and variables in final multi-variate model

	Uni-variate analysis			Final model of multi-variate analysis^b
Variable	Unstandardized B	p	95 % CI for B	Unstandardized B	p	95 % CI for B
Age (per 10 year)	0.023	0.08	−0.004 ÷ 0.05	0.021	0.06	−0.002 ÷ 0.04
PU mean (per 1 g/day)	−0.061	0.08	−0.13 ÷ 0.09	−0.065	0.06	−0.14 ÷ 0.005
PU max (per 1 g/day)	−0.023	0.38	−0.004 ÷ 0.05	–	–	–
Albumin (per 0.1 g/dl)	−0.061	0.21	−0.04 ÷ 0.16	–	–	–
Phosphate (per 0.1 mmol/l)	0.015	0.18	−0.008 ÷ 0.04	0.016	0.08	−0.003 ÷ 0.03
Hb (per 1 g/dl)	0.018	0.32	−0.02 ÷ 0.06	–	–	–
ln CRP (per 0.1 mg/dl^a)	−0.039	0.14	−0.09 ÷ 0.15	–	–	–
Categorical variable comparisons				Categorical variable in equation
Glom. v. interst.	−0.082 ± 0.035	0.06	−0.059 ± 0.044	−0.016	0.06	−0.003 ÷ 0.03
Female v. male	−0.079 ± 0.025	0.11	−0.066 ± 0.024	−0.013	0.03	−0.003 ÷ − 0.001
DM v. non-DM	−0.072 ± 0.021	0.50	−0.069 ± 0.023	–	–	–

CI confidence interval, PU proteinuria, g/day, mean averaged for study period, max maximum per study period, Hb hemoglobin, CRP C-reactive protein, glom. glomerular diseases, interst. interstitial diseases, DM diabetes mellitus
^aBefore ln-transformation
^bp for exclusion from model 0.10

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