Fig 1

LPS or ADR induced podocyte apoptosis. a-d Podocytes were stained with Annexin V/PI for flow cytometry analysis. Cell apoptosis rate was significantly increased in LPS or ADR treated podocytes comparing to normal controls. e Bax mRNA expression was increased in LPS or ADR treated podocytes. f-g Bax protein expression was increased in LPS or ADR treated podocytes. Results were expressed as fold Bax of LPS or ADR group in relation to controls normalized to GAPDH. All data were from at least three independent experiments. * P < 0.05 vs controls