Table 2 Univariate analysis of factors associated with potential drug-drug interactions
From: Evaluation of potential drug- drug interactions among Palestinian hemodialysis patients
Characteristic | Frequency % N = 275 | Number of DDIs Median (Q1-Q3) | P-value |
|---|---|---|---|
Gender | |||
Male | 151 (54.9) | 3 (1–5) | 0.725a |
Female | 124 (45.1) | 3 (1.25–5) | |
Age category | |||
<30 | 40 (14.5) | 2 (1–3) | 0.015b |
30–60 | 151 (54.9) | 3 (1–5) | |
>60 | 84 (30.5) | 3 (2–5) | |
Smoker | |||
Yes | 58 (21.1) | 3 (1–5) | 0.834a |
No | 217 (78.9) | 3 (1–5) | |
Duration of dialysis (years) | |||
<4 | 203 (73.8) | 3 (1–5) | 0.920a |
≥4 | 72 (26.2) | 3 (2–4) | |
Total chronic co-morbid disease | |||
None | 36 (13.1) | 1 (1–3) | <0.001b |
1 | 96 (34.9) | 2.5 (1–4) | |
2 | 90 (32.7) | 3 (1.75–5) | |
≥3 | 53 (19.3) | 4 (2–7) | |
Total number of medications | |||
<5 | 26 (9.5) | 1 (0.0–1) | <0.001a |
≥5 | 249 (90.5) | 3 (1–5) | |