Table 2 Screening and treatment of chronic renal patients colonized with S. areus on peritoneal dialysis
Author | Year | Design | Pacient (n.) | NCSA (n./%) | Treatment | Follow up | Erradication | ESI | Peritonitis | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Treated group | Control group | Treated group | Control group | Treated group | Control group | Treated group | Control group | Treated group | Control group | Treated group | Control group | ||||
Mupirocin Study Group [16] | 1996 | DCR | 134 | 133 | 18 | 24 | Nasal mupirocin 2x/day for 5 days every 4 weeks | Placebo | 18 months | 18 months | 90 % | 14 | 44 | 18 | 24 |
Wong [17] | 2003 | ECR | 73 | 81 | 16 | 14 | CESS mupirocin 1x/d | No treatment | 5 months | 5 months | NT | 0 | 10 | 1 | 1 |
Zimmerman [18] | 1991 | ECR | 32 | 32 | 9 | 8 | Oral rifampicin 300 mg 2x/d for 5d every 3 months | No treatment | 10 months | 12 months | NT | 3 | 12 | 3 | 5 |
Lye [19] | 1994 | ECR | 41 | 105 | 3 | 6 | Cefazolin + CESS gentamicin | No treatment | 36 months | 36 months | NT | 2 | 4 | 2 | 0 |
Sesso [20] | 1998 | ECR | 9 | 13 | 5 | 5 | Nasal and CESS sodium fusidate | No treatment | 7,8 months | 7,8 months | 43 % | 3 | 5 | 1 | 6 |
Sesso [20] | 1998 | ECR | 13 | 5 | 5 | Oral Ofloxacin (dd) | No treatment | 7,8 months | 7,8 months | 40 % | 2 | 5 | 4 | 6 | |
Bernardini [21] | 2005 | ECR | 67 | 66 | 9 | 9 | CESS mupirocin 2x/d for 5d every 3 months | CESS gentamicin 2x/d for 5d every 3 months | 8 months | 8 months | 97 % | 0 | 10 | 1 | 1 |
Fontán [22] | 1993 | ECR | 12 | 10 | 12 | 10 | Nasal mupirocina for 7 d | Nasal neomicin for 7 d | 9,5 months | 9,5 months | 100 % | 1 | 1 | 0 | 1 |
Bernardini [23] | 1996 | ECR | 41 | 41 | 18 | 18 | CESS mupirocin daily | Oral Rifampicin 600 mg 1x/d for 5d every 3 months | months | 12 months | NT | 5 | 6 | 2 | 1 |
Cavdar [24] | 2004 | ECR | 18 | 18 | 3 | 0 | CESS mupirocin 3x/week | CESS mupirocin 1x/week | 6 months | 6 months | 83 % | 0 | 1 | 0 | 1 |