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Fig. 4 | BMC Nephrology

Fig. 4

From: Blood pressure and proteinuria control remains a challenge in patients with type 2 diabetes mellitus and chronic kidney disease: experience from the prospective observational ALICE-PROTECT study

Fig. 4

Associated factors with BP and Pu control and cardiovascular and renal events occurrence. a Associated factors BP <140/90 mmHg at year 2. The following parameters (significant in univariate analysis) were included in the model : smoking status, BP control at baseline, antihypertensive score at baseline and at year 2, prescription of CCB, diuretics, antialdosterone or centrally acting drugs at baseline and at year 2, Pu level and severity of renal failure at year 2, diabetes control and history of retinopathy at baseline. b Associated factors with Pu < 0,5 g/day at year 2. The following parameters (significant in univariate analysis) were included in the model : age, BP control at year 2, Pu level and severity of renal failure at baseline, prescription of antialdosterone or centrally acting drugs treatment at baseline and year two. c Associated factors with renal events at year 2. The following parameters (significant in univariate analysis) were included in the model : BP control at baseline, Pu level and severity of renal failure at baseline and at year 2, the antihypertensive treatment score at year two, RAS blockade at baseline and year 2, prescription of CCB, diuretics, centrally acting drugs or statins at baseline and at year 2. d Associated factors with cardiovascular events at year 2. The following parameters (significant in univariate analysis) were included in the model : age, duration of hypertension and diabetes, CPAP-treated sleep apnoea, severity of renal failure at baseline and year 2, LDL cholesterol control at baseline, antihypertensive treatment score at baseline, RAS blockade at year 2, prescription of antiplatelet drugs, CCB, diuretics, betablockers or centrally acting drugs at baseline and at year 2, history of CV disease at baseline (coronary heart disease, history of stroke, peripheral arterial disease of the lower extremities, or hospitalisation for heart failure)

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