Table 2 Adjusted hazard ratios of covariates for the multistate model

Age (per decade) _{stroke 1→ death}

1.24 – 1.29

<0.0001

Age (per decade) _{stroke 2→ death}

1.30 – 1.50

<0.0001

Female sex _{stroke 1→ stroke 2}

1.20 – 1.56

<0.0001

Race^a AA _{stroke 1→ death}

0.77 – 0.85

<0.0001

Race^a Other _{stroke 2→ death}

0.34 – 0.88

0.013

BMI^b <20 kg/m²_{stroke 1→ death}

1.11 – 1.28

<0.0001

BMI^b 25–29.9 kg/m²_{stroke 1→ death}

0.86 – 0.97

0.0012

BMI^b 25–29.9 kg/m²_{stroke 2→ death}

0.61 – 0.86

0.0002

BMI^b ≥30 kg/m²_{stroke 1→ death}

0.87 – 0.97

0.0038

BMI^b ≥30 kg/m²_{stroke 2→ death}

0.67 – 0.96

0.018

Diabetes _{stroke 1→ death}

1.02 – 1.12

0.0070

CHF _{stroke 1→ death}

1.14 – 1.24

<0.0001

PVD _{stroke 2→ death}

1.09 – 1.55

0.0044

Previous stroke^c_{stroke 1→ stroke 2}

1.00 – 1.29

0.052

Previous stroke^c_{stroke 1→ death}

0.52 – 0.57

<0.0001

Previous stroke^c_{stroke 2→ death}

0.54 – 0.72

<0.0001

Smoker _{stroke 2→ death}

1.50 – 3.03

<0.0001

Unemployed _{stroke 1→ death}

1.10 – 1.66

0.0040

Inability to amb _{stroke 1→ death}

1.09 – 1.36

0.0004

Inability to trans _{stroke 1→ death}

1.03 – 1.44

0.021

Subsequent stroke _{stroke 1→ death}^d

0.96 – 3.09

0.071