Table 5 Diagnosis, treatments and outcomes according to severity of hyponatraemia
All patients (n = 147) | Group A (n = 20) | Group B (n = 41) | Group C (n = 86) | P a | |
|---|---|---|---|---|---|
Diagnosis | |||||
Unknown (%) | 69 (46.9) | 6 (30.0) | 16 (39.0) | 47 (54.7) | .07 |
Potomania (%) | 8 (5.4) | 3 (15.0) | 3 (7.3) | 2 (2.3) | .04 |
Heart failure (%) | 13 (8.8) | 1 (5.0) | 2 (4.9) | 10 (11.6) | .37 |
Cirrhosis (%) | 4 (2.7) | 0 (0) | 1 (2.4) | 3 (3.5) | .68 |
Diuretics (%) | 6 (4.1) | 1 (5.0) | 1 (2.4) | 4 (4.7) | .82 |
Hypotonic fluids (%) | 3 (2.0) | 0 (0) | 1 (2.4) | 2 (2.3) | 1.0 |
Dehydration (%) | 22 (15.0) | 4 (20.0) | 7 (17.1) | 11 (12.8) | .61 |
CSWS (%) | 2 (1.4) | 0 (0) | 1 (2.4) | 1 (1.2) | .66 |
SIADH (%) | 28 (19.1) | 6 (30.0) | 12 (29.3) | 10 (11.6) | .03 |
Hypothyroidism (%) | 3 (2.0) | 2 (10.0) | 1 (2.4) | 0 (0) | .02 |
Adrenal insufficiency (%) | 4 (2.7) | 1 (5.0) | 0 (0) | 3 (3.5) | .42 |
Treatment (%) | 127 (86.4) | 20 (100) | 37 (90.2) | 70 (81.4) | .06 |
- Fluid restriction (%) - Cause withdrawal (%) - Isotonic saline (%) - Hypertonic saline (%) - Furosemide (%) - Demeclocycline (%) | 93 (63.3) 31 (21.1) 67 (45.6) 16 (10.9) 19 (12.9) 10 (6.8) | 17 (85.0) 8 (40.0) 8 (40.0) 9 (45.0) 2 (10.0) 4 (20.0) | 28 (68.3) 9 (22.0) 22 (53.7) 2 (4.9) 6 (14.6) 4 (9.8) | 48 (55.8) 14 (16.3) 37 (43.0) 5 (5.8) 11 (12.8) 2 (2.3) | .04 .07 .47 <.001 .94 .01 |
Plasma sodium normalisation (%) | 84 (57.1) | 12 (60.0) | 24 (58.5) | 48 (55.8) | .92 |
Death during hospitalisation (%) | 36 (24.5) | 2 (10.0) | 13 (31.7) | 21 (24.4) | .17 |
Death during follow-up (%) | 74 (50.3) | 8 (40.0) | 21 (51.2) | 45 (52.3) | .64 |