Skip to main content

Table 4 Risk factors associated with death and dialysis initiation (multivariable analyses). Covariates were selected in the multivariable analysis using a stepwise procedure adapted to multiple imputation methodology

From: Competing risk of death and end-stage renal disease in incident chronic kidney disease (stages 3 to 5): the EPIRAN community-based study

 

Death

 

Dialysis

Cox model

Fine-Gray model

Cox model

Fine-Gray model

HR

95 % CI

HR

95 % CI

HR

95 % CI

HR

95 % CI

Age (years)

Age (yrs)

  < 70

1.00

 

1.00

 

 < 70

1.00

 

1.00

 

 70 –80

1.85

[1.19 –2.89]

2.07

[1.32 –3.23]

 70 –80

0.34

[0.17 –0.65]

0.30

[0.16 –0.58]

 80 –85

1.78

[1.09 –2.91]

2.03

[1.24 –3.31]

 80 –85

0.33

[0.14 –0.81]

0.33

[0.14 –0.78]

  > 85

2.56

[1.64 –4.00]

2.84

[1.82 –4.43]

 > 85

0.53

[0.25 –1.10]

0.40

[0.18 –0.88]

Hemoglobin

Hemoglobin

  ≥ 11 g/dL

1.00

 

1.00

 

 ≥ 11 g/dL

1.00

 

1.00

 

  < 11 g/dL

2.18

[1.61 –2.93]

2.01

[1.49 –2.73]

 < 11 g/dL

2.05

[1.16 –3.60]

1.62

[0.92 –2.84]

Cancer < 5 years

    

eGFR

    

 No

1.00

 

1.00

 

 ≥ 20 mL/min

1.00

 

1.00

 

 Yes

1.61

[1.14 –2.28]

1.62

[1.1 –2.37]

 < 20 mL/min

8.13

[4.37 –15.13]

8.32

[4.4 –15.71]

Chronic Heart Failure

Diabetes

 No

1.00

 

1.00

 

 No

1.00

 

1.00

 

 Yes

1.72

[1.26 –2.34]

1.81

[1.31 –2.49]

 Yes

3.41

[1.92 –6.07]

3.43

[1.93 –6.09]

Stroke

 

 No

1.00

 

1.00

 

 Yes

1.46

[0.93 –2.28]

1.44

[0.89 –2.32]

High Blood Pressure

 No

1.00

 

1.00

 

 Yes

0.76

[0.55 –1.04]

0.80

[0.58 –1.11]

  1. CI confidence interval, HR hazard ratio