Association of peripheral arterial disease with all-cause and cardiovascular mortality in hemodialysis patients: a meta-analysis

Table 4 Subgroup meta-analysis for CV mortality

Subgroup	No. of studies	RR (95 % CI)	I² (%)	P ^a	P ^b
Study design
Prospective	4	4.45 (2.43, 8.16)	42.9	0.154	0.048
Retrospective	2	1.45 (1.22, 1.73)	0	0.478	0.048
Ascertainment of PAD with ABI only
Yes	3	3.87 (1.55, 9.63)	68.5	0.042	0.493
No	3	2.33 (1.15, 4.72)	76.7	0.014	0.493
Follow-up time, months
<62	3	6.33 (3.54, 11.32)	0	0.953	0.017
≥62	3	1.65 (1.22, 2.24)	33.4	0.223	0.017
Diabetes mullitus(%)
<29	3	4.07 (1.81, 9.16)	44.4	0.166	0.389
≥29	3	2.36 (1.07, 5.22)	85.4	0.001
PAD (%)
<26	4	2.33 (1.30, 4.17)	80.7	0.001	0.160
≥26	2	7.13 (2.76, 18.4)	0	0.994	0.160
Duration of dialysis, years
<6.9	2	6.20 (3.29, 11.67)	0	0.795	0.115
≥6.9	2	2.14(1.37, 3.34)	0	0.559

^aP value for heterogeneity within each subgroup. ^bP value for heterogeneity between subgroups in the meta-regression analysis

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