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Table 1 Baseline characteristics for entire cohort and for patients who reached and did not reach end-points

From: The importance of proteinuria and prior cardiovascular disease in all major clinical outcomes of atherosclerotic renovascular disease – a single-center observational study

 

All

Died

ESKD

CVE

Any

Test

 

n = 830

No (n = 226)

Yes (n = 604)

p

No (n = 658)

Yes (n = 172)

p

No (n = 520)

Yes (n = 310)

p

No (n = 148)

Yes (n = 682)

p

 

Median age (years)

71.0 (64.8–76.7)

68.6

72.1

<0.0001

71.5

70.2

0.1

71.4

70.4

0.1

69.1

71.4

0.01

MWU

Male (%)

59.9

59.3

60.1

0.8

59

63.4

0.3

58.1

62.9

0.2

57.4

60.4

0.5

X 2

RAS >70% unilateral (%)

39.5

35.0

41.2

0.1

38.8

42.4

0.4

41.5

36.1

0.1

35.1

40.5

0.2

X 2

RAS >70% Bilateral (%)

10.6

9.3

11.1

0.5

10.3

11.6

0.6

10.6

10.6

0.9

6.8

11.4

0.09

X 2

Median patency score

105.0 (70.0–150.0)

120.0

100.0

0.007

110.0

100.0

0.1

105.0

107.5

0.9

130.0

100.0

<0.0001

MWU

Median SBP mmHg

152.0 (135.0–175.3)

152.0

152.0

0.8

154.0

150.0

0.2

150.0

153.5

0.6

150.0

152.5

0.6

MWU

Median DBP mmHg

80.0 (70.0–90.0)

79.0

80.0

0.3

80.0

80.0

0.9

80.0

80.0

0.9

79.0

80.0

0.2

MWU

Median MAP mmHg

103.3 (93.3–115.3)

101.8

103.3

0.5

103.3

101.4

0.5

102.8

103.3

0.8

100.7

103.3

0.3

MWU

MVD (%)

71.8

63.3

75.0

0.001

71.7

72.1

0.9

68.5

77.4

0.006

60.1

74.3

<0.0001

X 2

CHF (%)

19.4

11.1

22.5

<0.0001

19.0

20.9

0.6

17.3

22.9

0.05

8.1

21.8

<0.0001

X 2

FPE (%)

6.4

4.4

7.1

0.2

6.2

7.0

0.7

5.6

7.7

0.2

4.1

6.9

0.2

X 2

Diabetes (%)

31.3

28.3

32.5

0.2

30.5

34.3

0.3

30.2

33.2

0.4

29.1

31.8

0.5

X 2

RAB (%)

50.0

66.4

43.9

<0.0001

52.1

41.9

0.02

49.6

50.6

0.8

64.9

46.8

<0.0001

X 2

BB (%)

37.1

43.4

34.8

0.02

35.9

41.9

0.1

37.5

36.5

0.8

44.6

35.5

0.04

X 2

CaB (%)

55.4

52.7

56.5

0.3

52.7

65.7

0.002

54.4

57.1

0.5

48.6

56.9

0.07

X 2

>3 anti-hypertensives (%)

48.1

54.9

45.5

0.02

47.6

50.0

0.6

45.8

51.9

0.09

53.4

46.9

0.2

X 2

Aspirin (%)

54.5

54.9

54.3

0.9

54.0

56.4

0.6

50.6

61.0

0.004

52.0

55.0

0.5

X 2

Statin (%)

55.9

69.9

50.7

<0.0001

56.1

55.2

0.8

54.8

57.7

0.4

68.2

53.2

0.001

X 2

Median Proteinuria (g/day)

0.6 (0.2–1.2)

0.3

0.6

<0.0001

0.4

1.0

<0.0001

0.5

0.6

0.2

0.2

0.6

<0.0001

MWU

Median eGFRa (ml/min/1.73 m2)

29.9 (19.3–43.2)

36.8

27.3

<0.0001

33.4

17.4

<0.0001

29.5

30.8

0.3

37.6

28.0

<0.0001

MWU

Revascularized (%)

17.5

19.9

16.6

0.3

16.9

19.8

0.4

14.8

21.9

0.009

13.5

18.3

0.2

X 2

  1. BB beta blocker, CaB calcium channel blocker, CHF congestive heart failure, CVE cardiovascular event, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, ESKD end-stage kidney disease, FPE flash pulmonary oedema, MAP mean arterial pressure, MVD macrovascular disease, MWU Mann Whitney U test, n number of patients, RAB renin-angiotensin blockade, RAS renal artery stenosis, SBP systolic blood pressure, X2 chi-square test. Bold data indicates a statistically significant difference with a p value less than 0.05
  2. aCalculated using Chronic Kidney Disease Epidemiology collaboration equation (CKD-EPI)11