Skip to main content

Table 2 Rate of eGFR decline per year for patients who reached clinical end-points and those who remained event-free

From: The importance of proteinuria and prior cardiovascular disease in all major clinical outcomes of atherosclerotic renovascular disease – a single-center observational study

 

All

Died

ESKD

CVE

Any

Yes (n = 400)

No (n = 201)

p

Yes (n = 108)

No (n = 493)

p

Yes (n = 244)

No (n = 357)

p

Yes (n = 469)

No (n = 132)

p

Median eGFR slopea (ml/min/1.73 m2/year)

(n = 601)

−0.9 (−3.0–0.9)

−1.1 (−3.5–1.2)

−0.6 (−2.2–0.8)

0.09

−2.0 (−4.6–−0.8)

−0.6 (−2.5–1.4)

<0.0001

−1.2 (−3.3–0.7)

−0.7 (−2.6–1.5)

0.02

−1.0 (−3.4–0.9)

−0.4 (−1.8–0.9)

0.01

 

Died (n = 400)

  

ESKD (n = 108)

  

CVE (n = 244)

  

Any (n = 469)

 

Revascularization status

NR (n = 517)

R (n = 84)

p

NR (n = 347)

R (n = 53)

p

NR (n = 91)

R (n = 17)

p

NR (n = 201)

R (n = 43)

p

NR (n = 397)

R (n = 72)

p

Median eGFR slopea(ml/min/1.73 m2/year)

−0.8 (−2.6–0.9)

−1.7 (−9.8–−1.7)

0.3

−1.0 (−3.2–0.9)

−1.5 (−11.2–7.6)

0.9

−2.1 (−4.6–−0.9)

−1.9 (−5.8–3.1)

0.9

−1.2 (−3.1–0.3)

1.4 (−9.3–5.9)

0.6

−1.0 (−3.2–0.9)

−1.6 (−9.8–5.8)

0.8

  1. CVE cardiovascular event, eGFR estimated glomerular filtration rate, eGFR estimated glomerular filtration rate calculated using Chronic Kidney Disease Epidemiology collaboration equation (CKD-EPI)11, ESKD end-stage kidney disease, MWU Mann Whitney U Test, n number of patients who met criteria for calculation of eGFR slope, NR non-revascularized, R revascularized. Bold data indicates a statistically significant difference with a p value less than 0.05
  2. aRepresenting rate of eGFR decline per year. This was calculated from slope of linear regression, excluding blood results taken during in-patient stay, patients who reached RRT, and patients with less than 1 year follow-up or less than 3 data points. For revascularized patients, only pre-revascularization serum creatinine values were entered into the analysis