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Table 3 Comparison of baseline characteristics between revascularized and non-revascularized patients

From: The importance of proteinuria and prior cardiovascular disease in all major clinical outcomes of atherosclerotic renovascular disease – a single-center observational study

 

All (n = 830)

Death (n = 604)

ESKD (n = 172)

CVE (n = 310)

Any (n = 682)

Non-revascularized (n = 685)

Revascularized (n = 145)

p

Non-revascularized (n = 504)

Revascularized (n = 100)

p

Non-revascularized (n = 138)

Revascularized (n = 34)

p

Non-revascularized (n = 242)

Revascularized (n = 68)

p

Non-revascularized (n = 557)

Revascularized (n = 125)

p

Median age (years)

71.6 (65.177.3)

69.2 (63.374.6)

0.001

72.1 (67.178.1)

69.5 (65.275.1)

0.002

70.4 (64.1–75.3)

68.5 (62.6–75.8)

0.4

71.3 (65.276.7)

68.5 (62.873.1)

0.007

71.9 (66.477.4)

69.2 (64.064.5)

<0.0001

Male (%)

61.2

53.8

0.1

61.5

53.0

0.1

64.5

58.8

0.5

64.0

58.8

0.4

61.2

56.8

0.4

RAS >70% unilateral (%)

38.2

45.5

0.1

40.5

45.0

0.4

42.8

41.2

0.9

35.1

39.7

0.5

39.7

44.0

0.4

RAS >70% Bilateral (%)

6.6

29.7

<0.0001

7.3

30.0

<0.0001

7.2

29.4

<0.0001

5.8

27.9

<0.0001

7.5

28.8

<0.0001

Median patency score

110.0 (90.0150.0)

75.0 (40.0120.0)

<0.0001

100.0 (80.0150.0)

72.5 (40.0115.0)

<0.0001

100.0 (73.8150.0)

82.5 (40.0120.0)

0.005

120.0 (80.0150.0)

75.0 (40.0110.0)

<0.0001

105.0 (132.0172.5)

75.0 (40.0120.0)

<0.0001

Median SBP (mmHg)

150.0 (133.5–172.0)

160.0 (139.0–186.0)

0.003

150.0 (132.3174.5)

160.0 (140.0185.8)

0.03

146.5 (132.0–166.8)

156.5 (140.0–177.8)

0.08

151.7 (134.8–175.0)

160.0 (139.3–185.8)

0.09

150.0 (132.0172.5)

160.0 (140.0186.0)

0.004

Median DBP (mmHg)

80.0 (70.090.0)

80.0 (72.090.0)

0.06

80.0 (70.0–90.0)

80.0 (72.0–89.5)

0.2

80.0 (70.0–86.0)

80.0 (70.0–86.5)

0.4

80.0 (70.0–89.0)

80.0 (75.0–89.5)

0.1

80.0 (70.0–90.0)

80.0 (72.7–90.0)

0.08

Median MAP (mmHg)

102.3 (93.0–114.3)

106.7 (96.7–120.0)

0.007

103.3 (92.7–116.6)

106.7 (96.7–118.1)

0.05

100.2 (93.2–113.1)

106.2 (96.6–118.0)

0.2

103.3 (93.3–114.2)

105.0 (96.8–120.5)

0.08

103.3 (92.5115.6)

106.7 (96.7120.0)

0.01

MVD (%)

70.4

78.6

0.05

73.6

82.0

0.08

71.7

73.5

0.8

75.2

85.3

0.08

72.7

81.6

0.04

CHF (%)

17.4

29.0

0.001

20.6

32.0

0.01

19.6

26.5

0.4

21.5

27.9

0.3

19.9

30.4

0.01

FPE (%)

5.4

11.0

0.01

6.3

11.0

0.1

6.5

8.8

0.6

7.0

10.3

0.4

6.1

10.4

0.09

Diabetes (%)

31.4

31.0

0.9

32.3

33.0

0.9

34.1

35.3

0.9

36.0

23.5

0.06

32.3

29.6

0.6

RAB (%)

49.9

50.3

0.9

43.5

46.0

0.6

41.3

44.1

0.8

51.7

47.1

0.5

46.5

48.0

0.8

BB (%)

36.2

41.4

0.2

34.3

37.0

0.6

40.6

47.1

0.5

35.5

39.7

0.5

34.5

40.0

0.2

CaB (%)

54.7

58.6

0.4

55.2

63.0

0.1

65.2

67.6

0.8

56.6

58.8

0.7

55.7

62.4

0.2

>3 anti-hypertensives (%)

47.3

51.7

0.3

45.2

47.0

0.7

50.7

47.1

0.7

53.3

47.1

0.4

46.5

48.8

0.6

Aspirin (%)

53.3

60.0

0.1

52.8

62.0

0.09

54.3

64.7

0.3

58.3

70.6

0.07

53.3

62.4

0.07

Statin (%)

55.3

58.6

0.5

49.8

55.0

0.3

53.6

61.8

0.4

58.3

55.9

0.7

52.4

56.8

0.4

Median Proteinuria (g/day)

0.6 (0.2–1.2)

0.4 (0.2–1.1)

0.3

0.6 (0.2–1.3)

0.5 (0.2–1.2)

0.2

1.0 (0.6–1.9)

0.7 (0.3–1.4)

0.1

0.6 (0.2–1.1)

0.6 (0.2–1.1)

0.4

0.6 (0.2–1.3)

0.5 (0.2–1.1)

0.1

Median eGFRa (ml/min/1.73 m2)

29.9 (18.8–43.2)

30.2 (20.0–43.4)

0.7

27.2 (16.7–40.5)

28.5 (17.3–37.7)

0.9

16.0 (9.3–26.8)

21.5 (10.3–30.5)

0.2

29.9 (19.4–44.5)

34.1 (23.0–45.4)

0.2

27.4 (17.2–41.3)

29.5 (19.6–40.1)

0.3

  1. BB beta blocker, CaB calcium channel blocker, CHF congestive heart failure, CVE cardiovascular event, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, ESKD end-stage kidney disease, FPE flash pulmonary oedema, MAP mean arterial pressure, MVD macrovascular disease, MWU Mann Whitney U test, n number of patients, RAB renin-angiotensin blockade, RAS renal artery stenosis, SBP systolic blood pressure, X2 Chi-square test. Bold data indicates a statistically significant difference with a p value less than 0.05
  2. aCalculated using Chronic Kidney Disease Epidemiology collaboration equation (CKD-EPI)11