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Table 1 Characteristics of patients enrolled at baseline of tacrolimus treatment

From: Evaluating tacrolimus treatment in idiopathic membranous nephropathy in a cohort of 408 patients

Items

Total (N = 408)

Age

39 ± 16

Male gender (N, %)

298 (73%)

eGFR a at baseline

105 ± 25

eGFR < 60

15 (3.7%)

Proteinuria (g/24 h)

6.2 (4.7–8.0)

Serum albumin (g/L)

24.6 ± 3.4

Months since renal disease onset

6.6 (3.1–13.1)

Months since renal biopsy

4.6 (0.1–6.2)

Average tacrolimus doses during induction treatment

0.047 mg/kg

Average tacrolimus exposure (ng/ml) b

4.7 ± 2.1

Combined with RASi§ treatment

283 (69.4%)

Combined with corticosteroids

383 (93.9%)

Previous treatment with immunosuppressive drugs

71 (17.4%)

  1. aeGFR, estimate glomerular filtration rate (mL/min/1.73 m2), calculated by CKD-EPI formula; bSix patients were not monitored blood level of tacrolimus during induction treatment; §RASi, angiotensin converting enzyme inhibitors and angiotensin II receptor blockers