Table 2 Surfactant protein D gene polymorphisms in AKI patients and healthy controls
Genotype/allele | AKI patients, n(%) | Controls, n(%) | Odds ratio (95% CI) | P value | AKI patients | Odds ratio (95% CI) | P value | |
|---|---|---|---|---|---|---|---|---|
Dead, n(%) | Alive, n(%) | |||||||
Met11Thr | ||||||||
Met/Met | 42 (26.4) | 51 (42.5) | 0.486 (0.293–0.805) | 0.007** | 9 (18.4) | 43 (39.1) | 0.351 (0.155–0.795) | 0.011 |
Met/Thr | 67 (42.1) | 54 (45.0) | 20 (40.8) | 47 (42.7) | ||||
Thr/Thr | 50 (31.5) | 15 (12.5) | 3.211 (1.699–6.067) | 0.001** | 20 (40.8) | 20 (18.2) | 3.103 (1.468–6.557) | 0.005** |
Allele | ||||||||
Met | 151 (47.5) | 156 (65.0) | 0.487 (0.345–0.687) | 38 (38.8) | 133 (60.5) | 0.414 (0.254–0.675) | ||
Thr | 167 (52.5) | 84 (35.0) | 2.054 (1.455–2.899) | 0.001** | 60 (61.2) | 87 (39.5) | 2.414 (1.482–3.933) | 0.0004** |
Ala160Thr | ||||||||
Ala/Ala | 70 (44.0) | 50 (41.7) | 1.101 (0.682–1.778) | 0.715 | 7 (14.3) | 15 (13.6) | 1.056 (0.401–2.779) | 0.913 |
Ala/Thr | 70 (44.0) | 50 (41.7) | 24 (49.0) | 50 (45.5) | ||||
Thr/Thr | 19 (12.0) | 20 (16.6) | 0.679 (0.344–1.337) | 0.297 | 18 (36.7) | 45 (40.9) | 0.839 (0.419–1.679) | 0.619 |
Allele | ||||||||
Ala | 210 (66.0) | 150 (62.5) | 1.167 (0.823–1.655) | 38 (38.8) | 80 (36.4) | 1.108 (0.679–1.810) | ||
Thr | 108 (34.0) | 90 (37.5) | 0.857 (0.604–1.216) | 0.422 | 60 (61.2) | 140 (63.6) | 0.902 (0.552–1.474) | 0.707 |