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Table 2 Patient characteristics and outcome of patients grouped by AKI definition and on positive urine output criteria alone or with serum creatinine criteria

From: Incidence, timing and outcome of AKI in critically ill patients varies with the definition used and the addition of urine output criteria

Definition

RIFLE (N = 326)

 

AKIN (N = 310)

 

KDIGO (N = 308)

 
 

UO only (N = 265)

UO and SCr (N = 61)

p-value

UO only (N = 230)

UO and SCr (N = 80)

p-value

UO only (N = 236)

UO and SCr (N = 72)

p-value

Characteristics of patients

 Age (years; mean (sd))

62 (15)

63 (15)

0.753

62 (15)

62 (15)

0.978

62 (15)

63 (14)

0.478

 Male sex (N (%))

173 (54)

34 (10)

0.185

149 (48)

45 (15)

0.182

153 (50)

41 (13)

0.265

 Body Mass Index (kg/m2; mean (sd))

27 (5)

26 (6)

0.184

27 (5.2)

26 (5.7)

0.051

27 (5.3)

26 (5.8)

0.118

 APACHE IV score (mean (sd))

54 (25)

75 (22)

0.000

52 (23)

72 (26)

0.000

52 (23)

74 (26)

0.000

Admission type

 • medical (N (%))

105 (32)

22 (6.7)

0.009

88 (28)

31 (10)

0.052

95 (31)

22 (7.1)

0.006

 • surgical

         

  ◦ scheduled (N (%))

124 (38)

21 (6.4)

 

112 (36)

30 (9.7)

 

112 (36)

30 (9.7)

 

  ◦ emergency (N (%))

36 (11)

18 (5.5)

 

30 (9.7)

19 (6.1)

 

29 (9.4)

20 (6.5)

 

Co morbidity

 • diabetes mellitus (N (%))

47 (14)

11 (3.4)

1

40 (13)

12 (3.9)

0.729

41 (13)

11 (3.6)

0.857

 • chronic kidney disease (N (%))

3 (0.9)

2 (0.6)

0.236

2 (0.6)

3 (0.9)

0.110

2 (0.6)

3

0.085

 • chronic dialysis (N (%))

0 (0)

0 (0)

na

0 (0)

0 (0)

na

0 (0)

(0.97) 0 (0)

na

ICU Length of stay (days; median [IQR])

3 [2–6]

6 [3–11]

0.000

3 [2–5]

6 [3–11]

0.000

3 [2–6]

5 [3–9.8]

0.000

ICU mortality (N (%))

13 (4.0)

6 (1.8)

0.139

8 (2.6)

11 (3.5)

0.002

10 (3.2)

9 (2.9)

0.021

Hospital mortality (N (%))

24 (7.4)

13 (4.0)

0.012

17 (5.5)

19 (6.1)

0.000

19 (6.2)

17 (5.5)

0.001

  1. RIFLE ‘risk’, ‘injury’, ‘failure’, ‘loss’ and ‘end-stage’ definition
  2. AKIN acute kidney injury network definition
  3. KDIGO kidney disease improving global outcome definition
  4. UO urine output. SCr: serum creatinine
  5. N number of patients
  6. P-value difference between patients with only urine output criteria positive and patients with both criteria positive