From: Factors affecting the long-term outcomes of idiopathic membranous nephropathy
Conservative management (N = 30) | Oral corticosteroid (N = 22) | Oral corticosteroid + cyclophosphamide (N = 100) | Oral corticosteroid + cyclosporine (N = 14) | |
---|---|---|---|---|
Agea (years) | 51 | 47 | 57 | 44 |
SBP (mmHg) | 128 | 125 | 130 | 135 |
Proteinuriaa(g/g creatinine) | 6.43 | 6.95 | 8.93 | 8.53 |
Serum Albumina(g/dL) | 2.8 | 2.5 | 2.3 | 2.3 |
Serum creatinine (mg/dl) | 0.91 | 0.93 | 1.03 | 0.92 |
Total cholesterola(mg/dl) | 277 | 354 | 354 | 321 |
Treatments | ||||
RAAS blockers | 26 (86.7%) | 13 (59.1%) | 75 (75%) | 12 (85.7%) |
Anti-HTN | 13 (43.3%) | 11 (50%) | 51 (51%) | 7 (50%) |
Statin | 22 (73.3%) | 10 (45.5%) | 79 (79%) | 12 (85.7%) |
Remission | 26 (86.7%) | 17 (77.2%) | 73 (73%) | 9 (64.3%) |
Relapse | 2/26 (7.7%) | 3/17 (17.6%) | 16/73 (21.9%) | 5/9 (55.6%) |
Persistence | 4 (13.4%) | 5 (22.8%) | 27 (27%) | 5 (35.7%) |
End pointsb | 2 (6.7%) | 4 (18.2%) | 13 (13%) | 3 (21.4%) |