Fig. 2

Renal biopsy: membranous glomerulonephritis and highlighting of IgG and C3d immune complexes’ deposits. 1) Hematoxylin Eosin × 4: red arrows show abnormal glomeruli. Green arrow shows normal glomerulus (nevertheless capsular fibrosis is observed). Purple arrow shows normal tubuli. 2) Highlighting of IgG’s deposits × 20: red arrows surround pathological glomerulus. IgG’s deposits in this glomerulus show more contrast than surrounding tissues. 3) Highlighting of C3d immune complexes’ deposits × 20: red arrows point to pathological glomerulus which shows more contrast than surrounding tissues because of C3d immune complexes’ deposits. 4) Immersion M + × 100: red arrow shows membranous glomerulonephritis’s typical thickening of glomerular basement membrane. This thickening is due to reaction against IgG and C3d’s deposits