Fig. 1From: Combined proximal tubulopathy, crystal-storing histiocytosis, and cast nephropathy in a patient with light chain multiple myelomaLight microscopic features of proximal tubulopathy, histiocytosis, and cast nephropathy. a Segmental sclerosis of glomerulus (Periodic acid-Schiff). b Eosinophilic cuboid and rhomboid crystals (arrows) in the cytoplasm of proximal tubular epithelial cells. c Giant cell reaction around the casts and obstructed distal tubule with fractured dense cast (arrows). d Many mononuclear and multinuclear cells (arrows) in the renal interstitium (hematoxylin and eosin)Back to article page