Table 2 [TIMP-2]•[IGFBP7] operating characteristics at 4 h after ICU admission for prediction of AKI
From: Urinary TIMP-2 and IGFBP7 for the prediction of acute kidney injury following cardiac surgery
A. Endpoint is any AKI | ||||
[TIMP-2]•[IGFBP7] Cutoff | Sensitivity | Specificity | NPV | PPV |
0.3 | 0.75 (0.51–0.91) | 0.70 (0.53–0.84) | 0.84 (0.66–0.95) | 0.58 (0.37–0.77) |
0.5 | 0.50 (0.27–0.73) | 0.84 (0.68–0.94) | 0.76 (0.60–0.88) | 0.63 (0.35–0.85) |
1.0 | 0.20 (0.06–0.44) | 0.95 (0.82–0.99) | 0.69 (0.54–0.81) | 0.67 (0.22–0.96) |
2.0 | 0.20 (0.06–0.44) | 1.00 (0.91–1.00) | 0.70 (0.56–0.82) | 1.00 (0.40–1.00) |
B. Endpoint is stage 2–3 AKI | ||||
0.3 | 1.00 (0.54–1.00) | 0.61 (0.46–0.74) | 1.00 (0.89–1.00) | 0.23 (0.09–0.44) |
0.5 | 0.67 (0.22–0.96) | 0.76 (0.63–0.87) | 0.95 (0.83–0.99) | 0.25 (0.07–0.52) |
1.0 | 0.33 (0.04–0.78) | 0.92 (0.81–0.98) | 0.92 (0.81–0.98) | 0.33 (0.04–0.78) |
2.0 | 0.33 (0.04–0.78) | 0.96 (0.87–1.00) | 0.92 (0.82–0.98) | 0.50 (0.07–0.93) |