Progression of chronic kidney disease: an illness-death model approach

BMC Nephrology

Table 2 Prognostic factors of kidney failure and death through three transitions: Illness-death model

Transitions	Factors	Coefficients	SE	Z	P > \|t\|	HR	LL	UL
CKD➔Death	Age	0.0497	0.0013	37.31	<0.001	1.051	1.048	1.054
	Male/Female	0.3861	0.0277	13.938	<0.001	1.471	1.393	1.553
	BMI	-0.0542	0.0038	−14.308	<0.001	0.947	0.940	0.954
	HDL	-0.0052	0.0017	−3.033	0.002	0.995	0.991	0.998
	DM	0.2034	0.0302	6.736	<0.001	1.226	1.155	1.300
	HT	-0.0902	0.031	−2.909	0.004	0.914	0.860	0.971
	CVD	0.5651	0.0333	16.959	<0.001	1.760	1.648	1.878
	RAS	-0.0734	0.0393	−1.868	0.062	0.929	0.860	1.004
CKD➔Kidney failure	Age	−0.0007	0.0012	−0.601	0.548	0.999	0.997	1.002
	Male/Female	−0.0815	0.0317	−2.574	0.01	0.922	0.866	0.981
	BMI	-0.0608	0.004	−15.355	<0.001	0.941	0.934	0.948
	HDL	-0.0143	0.0019	−7.422	<0.001	0.986	0.982	0.990
	DM	0.1264	0.0318	3.979	<0.001	1.135	1.066	1.208
	HT	0.0836	0.0333	2.51	0.012	1.087	1.018	1.161
	CVD	-0.0998	0.0462	−2.16	0.031	0.905	0.827	0.991
	RAS	-0.4301	0.0449	−9.582	<0.001	0.650	0.596	0.710
Kidney failure➔death	Age	0.0051	0.0017	3.036	0.002	1.005	1.002	1.008
	Male/Female	0.2598	0.0391	6.651	<0.001	1.297	1.201	1.400
	BMI	-0.023	0.0049	−4.647	<0.001	0.977	0.968	0.987
	HDL	0.001	0.0019	0.545	0.586	1.001	0.997	1.005
	DM	0.4741	0.0404	11.744	<0.001	1.607	1.484	1.739
	HT	0.2403	0.0416	5.769	<0.001	1.272	1.172	1.380
	CVD	0.3554	0.0558	6.373	<0.001	1.427	1.279	1.592
	RAS	0.0974	0.0551	1.769	0.077	1.102	0.990	1.228

ISSN: 1471-2369