Table 2 Characteristics between matched septic patients with and without AKI
Variables | Non-AKI n = 784 | AKI n = 784 | p- value | Standardized difference(%) |
|---|---|---|---|---|
Male gender | 504 (64.3%) | 504 (64.3%) | 1.000 | 10.5 |
Age (years) | 64 (49–76) | 64 (49–77) | 0.578 | 6.5 |
BMI (kg/m2) | 23.1 (20.8–24.9) | 23.0 (20.8–25.1) | 0.950 | 13.5 |
Chronic comorbidities | ||||
COPD/asthma | 62 (7.9%) | 62 (7.9%) | 1.000 | 8.3 |
Cardiovascular disease | 107 (13.7%) | 107 (13.7%) | 1.000 | 8.1 |
Hypertension | 230 (29.3%) | 226 (28.8%) | 0.824 | 1.6 |
Diabetes | 138 (17.6%) | 138 (17.6%) | 1.000 | 1.0 |
Cancer | 77 (9.8%) | 76 (9.7%) | 0.932 | 0.3 |
Chronic liver disease | 11 (1.4%) | 14 (1.8%) | 0.545 | 19.2 |
APACHE II score | 18 (13–23) | 18 (13–23) | 0.654 | 16.6 |
Non-renal SOFA score | 6 (4–9) | 6 (4–9) | 0.473 | 18.7 |
Baseline creatinine | 76 (64–87) | 76 (65–88) | 0.539 | 9.4 |
Mechanical ventilation | 592 (75.5%) | 611 (77.9%) | 0.256 | 17.5 |
Use of nephrotoxic drugs | 61 (7.8%) | 70 (8.9%) | 0.411 | 4.6 |
Septic shock | 311 (39.7%) | 333 (42.5%) | 0.259 | 5.5 |
MAP (mmHg) | 78 (65–93) | 77 (64–92) | 0.565 | 13.8 |