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Table 2 Cox proportional hazard regression analysis showing the relationship of ASCVD risk trajectories with incident chronic kidney disease

From: Trajectories of atherosclerotic cardiovascular disease risk scores as a predictor for incident chronic kidney disease

 

Stable ASCVD risk

Increasing ASCVD risk

Total cases, n

4218

814

Incident CKD cases, n

322

127

Follow-up time, person-year

40,492.7

7536.8

Incident rate per 1000 person-year

7.95

16.85

  

HR

95% CI

p

Unadjusted

1 (reference)

2.13

1.74–2.62

 < 0.001

Model 1

1 (reference)

1.39

1.06–1.82

0.016

Model 2

1 (reference)

1.35

1.02–1.77

0.033

Model 3

1 (reference)

1.35

1.02–1.78

0.033

  1. Model 1: Adjusted for sex, age groups, BMI, total energy intake, smoking status, alcohol drinking status, and physical activity
  2. Model 2: Adjusted for variables used in Model 1 plus MBP, FPG, serum total cholesterol, and CRP levels
  3. Model 3: Adjusted for variables used in Model 2 plus baseline ASCVD risk scores and baseline eGFR
  4. Abbreviations: ASCVD atherosclerotic cardiovascular disease, CKD chronic kidney disease, BMI body mass index, MBP mean blood pressure, FPG fasting plasma glucose, CRP C-reactive protein, eGFR estimated glomerular filtration rate, HR hazard ratio, CI confidence interval
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BMC Nephrology

ISSN: 1471-2369

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